{{Rsnum
|rsid=2162440
|Chromosome=18
|position=37634043
|Orientation=minus
|GMAF=0.2833
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 64.6 | 28.3 | 7.1
| HCB | 65.7 | 31.4 | 2.9
| JPT | 56.6 | 40.7 | 2.7
| YRI | 25.2 | 53.7 | 21.1
| ASW | 26.3 | 49.1 | 24.6
| CHB | 65.7 | 31.4 | 2.9
| CHD | 60.2 | 33.3 | 6.5
| GIH | 36.6 | 48.5 | 14.9
| LWK | 16.4 | 50.0 | 33.6
| MEX | 72.4 | 27.6 | 0.0
| MKK | 25.6 | 49.4 | 25.0
| TSI | 50.0 | 44.1 | 5.9
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19359265
|Trait=Telomere length
|Title=A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length
|RiskAllele=G
|Pval=0.000003
|OA=1
}}

{{PharmGKB
|RSID=rs2162440
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:19359265; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: A genome-wide association study identifies a novel locus on chromosome 18q12.2 influencing white cell telomere length. (Initial Sample Size: 1,625 women; Replication Sample Size: 1,165 individuals); (Region: 18q12.2; Reported Gene(s): BRUNOL4, VPS34; Risk Allele: rs2162440-G); (p-value= 0.000003).This variant is associated with Telomere length.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739857
}}

{{omim
|id=609113
|rsnum=2162440
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2162440
|overall_frequency_n=79
|overall_frequency_d=128
|overall_frequency=0.617188
|n_genomes=48
|n_genomes_annotated=0
|n_haplomes=71
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=24349443
|Title=Association of TERC and OBFC1 Haplotypes with Mean Leukocyte Telomere Length and Risk for Coronary Heart Disease
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}