{{Rsnum
|rsid=2171492
|Gene=CPA4
|Chromosome=7
|position=130310900
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=T
|GMAF=0.3292
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=CPA4
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 38.9 | 53.1 | 8.0
| HCB | 32.1 | 51.1 | 16.8
| JPT | 47.8 | 41.6 | 10.6
| YRI | 65.1 | 34.2 | 0.7
| ASW | 50.9 | 33.3 | 15.8
| CHB | 32.1 | 51.1 | 16.8
| CHD | 28.4 | 56.9 | 14.7
| GIH | 50.5 | 39.6 | 9.9
| LWK | 61.8 | 30.9 | 7.3
| MEX | 58.6 | 31.0 | 10.3
| MKK | 59.0 | 35.3 | 5.8
| TSI | 40.2 | 38.2 | 21.6
| HapMapRevision=28
}}[http://news.google.com/news/url?sa=t&ct2=us%2F1_0_s_0_0_t&usg=AFQjCNGg8_lAmCgbeVktaQFug38X9J4rkw&sig2=ChUbC_BLiG-nC_w1FGbytw&cid=0&ei=I-CnSbjnD-GPmAeF6tGmAw&url=http%3A%2F%2F7thspace.com%2Fheadlines%2F304386%2Fcarboxypeptidase_4_gene_variants_and_early_onset_intermediate_to_high_risk_prostate_cancer.html news] (rs2171492, Cys303Gly) in CPA4 was associated with an increased risk of aggressive [[prostate cancer]] among younger ...

{{PMID Auto
|PMID=19245716
|Title=Carboxypeptidase 4 gene variants and early-onset intermediate-to-high risk prostate cancer.
|OA=1
}}

{{PMID Auto
|PMID=22144497
|Title=Assessing the clinical role of genetic markers of early-onset prostate cancer among high-risk men enrolled in prostate cancer early detection
|OA=1
}}

{{PMID Auto
|PMID=20205905
|Title=Association of repeatedly measured intermediate risk factors for complex diseases with high dimensional SNP data.
|OA=1
}}

{{PMID Auto
|PMID=20403199
|Title=High-throughput analysis of candidate imprinted genes and allele-specific gene expression in the human term placenta.
|OA=1
}}

{{GET Evidence
|gene=CPA4
|aa_change=Gly270Cys
|aa_change_short=G270C
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2171492
|n_genomes=1
|n_genomes_annotated=0
|n_haplomes=1
|n_articles=0
|n_articles_annotated=0
|nblosum100=7
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}