{{Rsnum
|rsid=2177369
|Gene=CHAT
|Chromosome=10
|position=50843729
|Orientation=minus
|GMAF=0.2787
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}
A case-control study of 471 Italian late-onset [[Alzheimer's disease]] patients aged 60 years or older, and 254 subjects with no neurodegenerative disorders serving as the control group, found that the [[rs2177369]](G;G) genotype (in dbSNP orientation) a risk factor with an odds ratio of 1.56 (CI: 1.10-2.22, p = 0.01). Refreshingly, the authors call their results "far from definitive".{{PMID|18780301}}

{{PMID Auto
|PMID=16223550
|Title=Genetic variation in the choline acetyltransferase (CHAT) gene may be associated with the risk of Alzheimer's disease.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}