{{Rsnum
|rsid=2221903
|Gene=IL21
|Chromosome=4
|position=122617757
|Orientation=minus
|GMAF=0.1997
|Gene_s=IL21
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 39.8 | 47.8 | 12.4
| HCB | 73.0 | 25.5 | 1.5
| JPT | 76.8 | 23.2 | 0.0
| YRI | 91.8 | 8.2 | 0.0
| ASW | 91.2 | 8.8 | 0.0
| CHB | 73.0 | 25.5 | 1.5
| CHD | 78.7 | 20.4 | 0.9
| GIH | 69.3 | 27.7 | 3.0
| LWK | 86.4 | 13.6 | 0.0
| MEX | 69.0 | 27.6 | 3.4
| MKK | 69.2 | 29.5 | 1.3
| TSI | 50.0 | 39.2 | 10.8
| HapMapRevision=28
}}{{PMID Auto
|PMID=23354321
|Title=IL21 and IL21R polymorphisms and their interactive effects on serum IL-21 and IgE levels in patients with chronic hepatitis B virus infection
}}

{{PMID Auto
|PMID=24389496
|Title=Interleukin (IL)-21 promoter polymorphism increases the risk of thyroid cancer in Chinese population
}}

{{PMID Auto
|PMID=24434811
|Title=The association of Interleukin-21 polymorphisms with Interleukin-21 serum levels and risk of systemic lupus erythematosus
}}

{{PMID Auto
|PMID=17720724
|Title=Genetic association of interleukin-21 polymorphisms with systemic lupus erythematosus.
}}

{{PMID Auto
|PMID=20553587
|Title=Only one independent genetic association with rheumatoid arthritis within the KIAA1109-TENR-IL2-IL21 locus in Caucasian sample sets: confirmation of association of rs6822844 with rheumatoid arthritis at a genome-wide level of significance.
|OA=1
}}

{{PMID Auto
|PMID=20652041
|Title=Interleukin-21: a new mediator of inflammation in systemic lupus erythematosus.
|OA=1
}}

{{PMID Auto
|PMID=22752563
|Title=A single nucleotide polymorphism of IL-21 gene is associated with systemic lupus erythematosus in a Chinese population.
}}

{{PMID Auto
|PMID=23288348
|Title=IL-21 gene polymorphism is associated with the prognosis of breast cancer in Chinese populations.
}}

{{PMID Auto
|PMID=25074442
|Title=Association of IL-21 polymorphisms (rs907715, rs2221903) with susceptibility to multiple autoimmune diseases: A meta-analysis
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}