{{Rsnum
|rsid=2227310
|Gene=CASP7
|Chromosome=10
|position=115489152
|Orientation=plus
|GMAF=0.2704
|Assembly=GRCh37
|GenomeBuild=37.1
|dbSNPBuild=131
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
}}
{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 52.2 | 39.8 | 8.0
| HCB | 33.3 | 51.9 | 14.8
| JPT | 24.8 | 49.6 | 25.7
| YRI | 78.9 | 18.4 | 2.7
| ASW | 82.5 | 15.8 | 1.8
| CHB | 33.3 | 51.9 | 14.8
| CHD | 32.1 | 48.6 | 19.3
| GIH | 57.4 | 41.6 | 1.0
| LWK | 68.2 | 30.9 | 0.9
| MEX | 50.9 | 40.4 | 8.8
| MKK | 71.8 | 26.3 | 1.9
| TSI | 62.0 | 33.0 | 5.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=19058873
|Title=Polymorphisms in the Caspase7 gene and the risk of lung cancer
}}

{{PMID Auto
|PMID=19826114
|Title=Polymorphisms in the CASPASE genes and survival in patients with early-stage non-small-cell lung cancer
}}

{{PMID Auto
|PMID=20567846
|Title=RIPK1 and CASP7 polymorphism as prognostic markers for survival in patients with colorectal cancer after complete resection
}}

{{PMID Auto
|PMID=22441531
|Title=Association of CASP7 Polymorphisms and Survival of Non-Small-Cell Lung Cancer Patients with Platinum-Based Chemotherapy Treatment
}}

{{PMID|16385451|OA=1
}} A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease.

{{PMID|17504820}} Caspase 7 influences susceptibility to rheumatoid arthritis.

{{PMID|19604093|OA=1
}} Genetic polymorphisms, their allele combinations and IFN-beta treatment response in Irish multiple sclerosis patients.

{{PMID|20661084}} Polymorphisms in the caspase genes and the risk of lung cancer.

{{GET Evidence
|gene=CASP7
|aa_change=Asp288Glu
|aa_change_short=D288E
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2227310
|overall_frequency_n=2303
|overall_frequency_d=10758
|overall_frequency=0.214073
|n_genomes=25
|n_genomes_annotated=0
|n_haplomes=28
|n_articles=0
|n_articles_annotated=0
|nblosum100=-2
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23765963
|Title=HuGE systematic review and meta-analysis demonstrate association of CASP-3 and CASP-7 genetic polymorphisms with cancer risk
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}