{{Rsnum
|rsid=2227684
|Gene=SERPINE1
|Chromosome=7
|position=101133650
|Orientation=plus
|GMAF=0.4353
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=SERPINE1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 15.9 | 54.0 | 30.1
| HCB | 19.7 | 50.4 | 29.9
| JPT | 23.9 | 61.1 | 15.0
| YRI | 25.9 | 44.9 | 29.3
| ASW | 29.8 | 42.1 | 28.1
| CHB | 19.7 | 50.4 | 29.9
| CHD | 23.9 | 41.3 | 34.9
| GIH | 10.9 | 55.4 | 33.7
| LWK | 6.4 | 50.9 | 42.7
| MEX | 7.0 | 38.6 | 54.4
| MKK | 10.4 | 45.5 | 44.2
| TSI | 24.5 | 45.1 | 30.4
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs2227684
|Name_s=
|Gene_s=SERPINE1
|Feature=
|Evidence=PubMed ID:18794724
|Annotation=The G allele of this variant is more frequent in patients with major depressive disorders (MDD) than in controls in a study consisting of 188 Chinese MDD patients and 346 controls.
|Drugs=
|Drug Classes=
|Diseases=Depression; Depressive Disorder, Major
|Curation Level=Curated
|PharmGKB Accession ID=PA162370400
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2227684
|overall_frequency_n=4900
|overall_frequency_d=10758
|overall_frequency=0.455475
|n_genomes=39
|n_genomes_annotated=0
|n_haplomes=53
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}