{{Rsnum
|rsid=2228044
|Gene=IL6ST
|Chromosome=5
|position=55968325
|Orientation=minus
|GMAF=0.1873
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=IL6ST
}}{{PMID Auto
|PMID=17664290
|Title=Signal transducer of inflammation gp130 modulates atherosclerosis in mice and man.
|OA=1
}}

{{PMID Auto
|PMID=18223637
|Title=A polymorphism at the IL6ST (gp130) locus is associated with traits of the metabolic syndrome.
}}

{{PMID Auto
|PMID=18603647
|Title=Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response.
|OA=1
}}

{{PMID Auto
|PMID=19401444
|Title=Body iron stores and glucose intolerance in premenopausal women: role of hyperandrogenism, insulin resistance, and genomic variants related to inflammation, oxidative stress, and iron metabolism.
|OA=1
}}

{{PMID Auto
|PMID=21981268
|Title=Lack of association of IL6R rs2228145 and IL6ST/gp130 rs2228044 gene polymorphisms with cardiovascular disease in patients with rheumatoid arthritis.
}}{{GET Evidence
|gene=IL6ST
|aa_change=Gly148Arg
|aa_change_short=G148R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2228044
|overall_frequency_n=2408
|overall_frequency_d=10756
|overall_frequency=0.223875
|n_genomes=28
|n_genomes_annotated=0
|n_haplomes=33
|n_articles=0
|n_articles_annotated=0
|nblosum100=6
|autoscore=0
|webscore=N
}}
{{PMID Auto
|PMID=22742541
|Title=No evidence of association between functional polymorphisms located within IL6R and IL6ST genes and systemic sclerosis
}}