{{Rsnum
|rsid=2229080
|Gene=DCC
|Chromosome=18
|position=52906232
|Orientation=plus
|ReferenceAllele=C
|MissenseAllele=G
|GMAF=0.4568
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=DCC
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 46.2 | 36.9 | 16.9
| HCB | 13.3 | 60.0 | 26.7
| JPT | 6.8 | 40.9 | 52.3
| YRI | 41.3 | 50.8 | 7.9
| ASW | 0.0 | 0.0 | 0.0
| CHB | 13.3 | 60.0 | 26.7
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

{{Venter SNP
|rsid=2229080
|allele=G
|frequency=0.35
|uid=1103645201050
|type=heterozygous_SNP
|hugo=DCC
|ensembl gene=ENSG00000187323
|ensembl transcript=ENST00000304775
|sift=TOLERATED
|disease=Colorectal tumors that lost their capacity to differentiate into mucus producing cells uniformly lack DCC expression. Inactivation of DCC due to allelic deletion and/or point mutations may cause both lymphatic and hematogenous metastasis of esophageal squamous cell carcinomas.
}}

{{GET Evidence
|gene=DCC
|aa_change=Arg201Gly
|aa_change_short=R201G
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2229080
|overall_frequency_n=3846
|overall_frequency_d=10758
|overall_frequency=0.357501
|n_genomes=38
|n_genomes_annotated=0
|n_haplomes=50
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.997
|nblosum100=6
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23353777
|Title=DCC (Deleted in Colorectal Carcinoma) Gene Variants Confer Increased Susceptibility to Gallbladder Cancer (Ref. No.: GENE-D-12-01446)
}}

{{PMID Auto
|PMID=23765761
|Title=Role of genetic variants of deleted in colorectal carcinoma (DCC) polymorphisms and esophageal and gastric cancers risk in Kashmir Valley and meta-analysis.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}