{{Rsnum
|rsid=2229857
|Gene=ADAR
|Chromosome=1
|position=154601491
|Orientation=minus
|ReferenceAllele=A
|MissenseAllele=G
|GMAF=0.3797
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=ADAR
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 10.7 | 43.8 | 45.5
| HCB | 11.2 | 47.8 | 41.0
| JPT | 8.0 | 39.3 | 52.7
| YRI | 42.2 | 46.9 | 10.9
| ASW | 45.6 | 42.1 | 12.3
| CHB | 11.2 | 47.8 | 41.0
| CHD | 1.9 | 41.7 | 56.5
| GIH | 5.1 | 35.7 | 59.2
| LWK | 39.4 | 48.6 | 11.9
| MEX | 3.6 | 30.4 | 66.1
| MKK | 27.6 | 50.6 | 21.8
| TSI | 11.9 | 34.7 | 53.5
| HapMapRevision=28
}}{{Venter SNP
|rsid=2229857
|allele=C
|frequency=0.333
|uid=1103675228835
|type=heterozygous_SNP
|hugo=ADAR
|ensembl gene=ENSG00000160710
|ensembl transcript=ENST00000368474
|sift=TOLERATED
|disease=Defects in ADAR are a cause of dyschromatosis symmetrica hereditaria (DSH) (MIM:127400); also known as reticulate acropigmentation of Dohi. DSH is a pigmentary genodermatosis of autosomal dominant inheritance characterized by a mixture of hyperpigmented and hypopigmented macules distributed on the dorsal parts of the hands and feet.
}}

{{ neighbor
| rsid = 1466731
| distance = 853
}}

{{PMID Auto
|PMID=21939710
|Title=Genetic polymorphisms in host antiviral genes: Associations with humoral and cellular immunity to measles vaccine
|OA=1
}}

{{PMID|19434718|OA=1
}} Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.

{{GET Evidence
|gene=ADAR
|aa_change=Lys89Arg
|aa_change_short=K89R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2229857
|n_genomes=1
|n_genomes_annotated=0
|n_haplomes=1
|n_articles=0
|n_articles_annotated=0
|nblosum100=-3
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Affy500k}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}