{{Rsnum
|rsid=2229940
|Gene=GABRA4
|Chromosome=4
|position=46993349
|Orientation=minus
|ReferenceAllele=C
|MissenseAllele=A
|GMAF=0.3407
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=GABRA4
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 3.2 | 48.4 | 48.4
| HCB | 11.6 | 51.2 | 37.2
| JPT | 0.0 | 58.1 | 41.9
| YRI | 1.6 | 37.7 | 60.7
| ASW | 0.0 | 0.0 | 0.0
| CHB | 11.6 | 51.2 | 37.2
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

{{PMID|18482426}} 1050 nicotine-dependent cases and 879 non-dependent [[smoking]] controls [[rs279858]] and [[rs16859834]] aka [[rs2229940]]

{{ neighbor
| rsid = 16859834
| distance = 1
}}

{{PMID Auto
|PMID=21422964
|Title=Gamma-aminobutyric acid GABRA4, GABRE, and GABRQ receptor polymorphisms and risk for essential tremor
}}

{{PMID Auto
|PMID=15024690
|Title=Variations in GABRA2, encoding the alpha 2 subunit of the GABA(A) receptor, are associated with alcohol dependence and with brain oscillations.
|OA=1
}}

{{PMID Auto
|PMID=16770606
|Title=Investigation of autism and GABA receptor subunit genes in multiple ethnic groups.
|OA=1
}}

{{PMID Auto
|PMID=19207358
|Title=Further evidence for an association between the gamma-aminobutyric acid receptor A, subunit 4 genes on chromosome 4 and Fagerstrom Test for Nicotine Dependence.
|OA=1
}}

{{GET Evidence
|gene=GABRA4
|aa_change=Leu26Met
|aa_change_short=L26M
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2229940
|overall_frequency_n=3574
|overall_frequency_d=10758
|overall_frequency=0.332218
|n_genomes=29
|n_genomes_annotated=0
|n_haplomes=34
|n_articles=0
|n_articles_annotated=0
|nblosum100=-3
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}