{{Rsnum
|rsid=2229992
|Gene=APC
|Chromosome=5
|position=112827157
|Orientation=plus
|GMAF=0.4674
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=APC
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 33.9 | 58.0 | 8.0
| HCB | 46.0 | 43.8 | 10.2
| JPT | 52.2 | 42.5 | 5.3
| YRI | 1.4 | 17.0 | 81.6
| ASW | 3.5 | 43.9 | 52.6
| CHB | 46.0 | 43.8 | 10.2
| CHD | 32.4 | 55.6 | 12.0
| GIH | 38.0 | 49.0 | 13.0
| LWK | 0.9 | 36.4 | 62.7
| MEX | 43.1 | 48.3 | 8.6
| MKK | 4.5 | 37.2 | 58.3
| TSI | 29.4 | 50.0 | 20.6
| HapMapRevision=28
}}{{PMID Auto
|PMID=21279955
|Title=Association of APC and MCC polymorphisms with increased breast cancer risk in an Indian population
}}
{{omim
|id=114500
|rsnum=2229992
}}

{{ClinVar
|rsid=2229992
|Reversed=0
|FwdREF=T
|FwdALT=C
|REF=T
|ALT=C
|RSPOS=112162854
|CHROM=5
|GMAF=0.4675
|dbSNPBuildID=98
|SSR=0
|SAO=1
|VP=0x05036800000017051f110101
|GENEINFO=APC:324
|GENE_NAME=APC
|GENE_ID=324
|WGT=0
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000005.9:g.112162854T>C
|CLNORIGIN=0
|CLNSIG=255
|CLNCUI=114500
|CLNDBN=AllHighlyPenetrant; Familial colorectal cancer
|Tags=PM;PMC;S3D;SLO;VLD;G5A;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.4674; 0.5326
|CLNACC=RCV000035064.2; RCV000074147.1
|CLNDSDB=MedGen; GeneReviews:MedGen:OMIM
|CLNDSDBID=CN169374; NBK1211:CN029768:114500
|COMMON=1
|Disease=AllHighlyPenetrant; Familial colorectal cancer
|CLNSRC=Emory University
|CLNSRCID=2625
}}

{{PMID Auto
|PMID=15768050
|Title=The tumor suppressor adenomatous polyposis coli gene is associated with susceptibility to schizophrenia.
}}

{{PMID Auto
|PMID=16569251
|Title=Single nucleotide polymorphisms of the APC gene and colorectal cancer risk: a case-control study in Taiwan.
|OA=1
}}

{{PMID Auto
|PMID=17221838
|Title=Association of adenomatous polyposis coli (APC) gene polymorphisms with autism spectrum disorder (ASD).
}}

{{PMID Auto
|PMID=17267408
|Title=Allelic imbalance in gene expression as a guide to cis-acting regulatory single nucleotide polymorphisms in cancer cells.
|OA=1
}}

{{PMID Auto
|PMID=18708403
|Title=Association of genetic variation in genes implicated in the beta-catenin destruction complex with risk of breast cancer.
|OA=1
}}

{{PMID Auto
|PMID=18849522
|Title=Nested Patch PCR enables highly multiplexed mutation discovery in candidate genes.
|OA=1
}}

{{PMID Auto
|PMID=20333795
|Title=APC gene mutations in Chinese familial adenomatous polyposis patients.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}