{{Rsnum
|rsid=2237895
|Gene=KCNQ1
|Chromosome=11
|position=2835964
|Orientation=plus
|GMAF=0.3476
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=KCNQ1
}}[http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.208.html nature] [[type-2 diabetes]] 
*[[rs2237895]], P = 7.3 times 10-9; OR = 1.32, 95% CI = 1.20â€“1.45
{{PMID Auto
|PMID=19366866
|Title=Association of type 2 diabetes candidate polymorphisms in KCNQ1 with incretin and insulin secretion
|OA=1
}}
{{PMID Auto
|PMID=19448982
|Title=Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China
|OA=1
}}
{{PMID Auto
|PMID=19516902
|Title=The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load
|OA=1
}}

{{PMID Auto
|PMID=19575309
|Title=Association study of four variants in KCNQ1 with type 2 diabetes mellitus and premature coronary artery disease in a Chinese population
}}
{{PMID Auto
|PMID=19584308
|Title=A variant in the KCNQ1 gene predicts future type 2 diabetes and mediates impaired insulin secretion
|OA=1
}}
{{PMID Auto
|PMID=19308350
|Title=Variations in KCNQ1 are associated with type 2 diabetes and beta cell function in a Chinese population
}}
{{PMID Auto
|PMID=19850681
|Title=Association of KCNQ1 Polymorphisms with the Gestational Diabetes Mellitus in Korean Women
}}

{{PMID Auto GWAS
|PMID=20174558
|Trait=Type 2 diabetes
|Title=A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese
|RiskAllele=C
|Pval=1E-9
|OR=1.29
|ORtxt=[1.19-1.40]
|OA=1
}}

{{PMID Auto
|PMID=22479571
|Title=Several Polymorphisms of KCNQ1 Gene Are Associated with Plasma Lipid Levels in General Chinese Populations
|OA=1
}}

{{PMID Auto
|PMID=22206064
|Title=KCNQ1 variants associate with type 2 diabetes in Malaysian Malay subjects
}}

{{PMID|18711366}} SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.

{{PMID|19207020|OA=1
}} Meta-analysis in genome-wide association studies.

{{PMID|19252135|OA=1
}} Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore.

{{PMID|19556355}} Common variants in KCNQ1 are associated with type 2 diabetes and impaired fasting glucose in a Chinese Han population.

{{PMID|20606385}} Polymorphisms in KCNQ1 are associated with gestational diabetes in a Korean population.

{{PMID|20701788|OA=1
}} KCNQ1 gene polymorphisms are associated with lipid parameters in a Chinese Han population.

{{PMID|21261977|OA=1
}} Variants in KCNQ1 increase type II diabetes susceptibility in South Asians: a study of 3,310 subjects from India and the US.

{{PMID|21278902|OA=1
}} Genetic risk profiling for prediction of type 2 diabetes.

{{PMID|21289621}} Effects of KCNQ1 polymorphisms on the therapeutic efficacy of oral antidiabetic drugs in Chinese patients with type 2 diabetes.

{{PMID|21291537|OA=1
}} Evidence for somatic gene conversion and deletion in bipolar disorder, Crohn's disease, coronary artery disease, hypertension, rheumatoid arthritis, type-1 diabetes, and type-2 diabetes.

{{PMID|21355884}} KCNQ1 gene variants and risk of new-onset diabetes in tacrolimus-treated renal-transplanted patients.

{{PMID|22414228}} KCNQ1 gene polymorphisms are associated with the therapeutic efficacy of repaglinide in Chinese Type 2 diabetic patients.

{{PMID|22461567|OA=1
}} Diabetes-associated common genetic variation and its association with GLP-1 concentrations and response to exogenous GLP-1.

{{PMID Auto
|PMID=23133642
|Title=The Association between KCNQ1 Gene Polymorphism and Type 2 Diabetes Risk: A Meta-Analysis
|OA=1
}}

{{PMID Auto
|PMID=23139357
|Title=Insights Into the Molecular Mechanism for Type 2 Diabetes Susceptibility at the KCNQ1 Locus From Temporal Changes in Imprinting Status in Human Islets
|OA=1
}}

{{PMID Auto
|PMID=23271129
|Title=Meta-analysis of the effect of KCNQ1 gene polymorphism on the risk of type 2 diabetes
}}

{{PMID Auto
|PMID=23029294
|Title=Meta-analysis of the relationship between common type 2 diabetes risk gene variants with gestational diabetes mellitus
|OA=1
}}

{{PMID Auto
|PMID=23786590
|Title=Common Variants in KCNQ1 Confer Increased Risk of Type 2 Diabetes and Contribute to the Diabetic Epidemic in East Asians: A Replication and Meta-Analysis
}}

{{PMID Auto
|PMID=22696034
|Title=KCNQ1 SNPS and susceptibility to diabetic nephropathy in East Asians with type 2 diabetes.
}}

{{PMID Auto
|PMID=22790062
|Title=Association between KCNQ1 genetic variants and obesity in Chinese patients with type 2 diabetes.
}}

{{PMID Auto
|PMID=23107108
|Title=Lack of association between genetic polymorphisms within KCNQ1 locus and type 2 diabetes in Tunisian Arabs.
}}

{{PMID Auto
|PMID=23334806
|Title=Systematic identification of interaction effects between genome- and environment-wide associations in type 2 diabetes mellitus.
|OA=1
}}

{{PMID Auto
|PMID=23462794
|Title=Identification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic islets.
|OA=1
}}

{{PMID Auto
|PMID=23630301
|Title=Strong parent-of-origin effects in the association of KCNQ1 variants with type 2 diabetes in American Indians.
}}

{{PMID Auto
|PMID=23692438
|Title=Association between KCNQ1 genetic variants and QT interval in a Chinese population.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}