{{Rsnum
|rsid=2238289
|Gene=HERC2
|Chromosome=15
|position=28208069
|Orientation=minus
|GMAF=0.4568
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=HERC2
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 0.0 | 21.9 | 78.1
| HCB | 55.6 | 42.2 | 2.2
| JPT | 70.5 | 25.0 | 4.5
| YRI | 68.3 | 28.6 | 3.2
| ASW | 0.0 | 0.0 | 0.0
| CHB | 55.6 | 42.2 | 2.2
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
[[rs2238289]] is part of a haplotype spanning 166kB on chromosome 15, defined by 13 SNPs listed below, found in 97% of all Caucasians with blue eyes. In this haplotype, variations in [[rs1129038]] and [[rs12913832]] are relatively common in Caucasians though rare among other ethnic groups.{{PMID|18172690}}

The "h-1" haplotype found in homozygous state in 97% of individuals with blue [[eye color]] is composed as follows {{PMID|18172690}}:

[[rs4778241]](C)<br>
[[rs1129038]](A)<br>
[[rs12593929]](A)<br>
[[rs12913832]](G)<br>
[[rs7183877]](C)<br>
[[rs3935591]](G)<br>
[[rs7170852]](A)<br>
[[rs2238289]](T)<br>
[[rs3940272]](C)<br>
[[rs8028689]](T)<br>
[[rs2240203]](A)<br>
[[rs11631797]](G)<br>
[[rs916977]](G)<br>

{{PMID|20042077|OA=1
}} Genetic determinants of hair and eye colours in the Scottish and Danish populations.

{{on chip | 23andMe v3}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}