{{Rsnum
|rsid=2239839
|Gene=DAXX
|Chromosome=6
|position=33320298
|Orientation=minus
|GMAF=0.2401
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=DAXX
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 52.2 | 38.1 | 9.7
| HCB | 60.0 | 35.6 | 4.4
| JPT | 59.3 | 35.4 | 5.3
| YRI | 98.6 | 1.4 | 0.0
| ASW | 82.5 | 17.5 | 0.0
| CHB | 60.0 | 35.6 | 4.4
| CHD | 58.7 | 36.7 | 4.6
| GIH | 42.6 | 48.5 | 8.9
| LWK | 0.0 | 0.0 | 0.0
| MEX | 31.0 | 53.4 | 15.5
| MKK | 98.7 | 1.3 | 0.0
| TSI | 49.0 | 42.2 | 8.8
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs2239839
|Name_s=intron 4 c.1252-74G>T
|Gene_s=DAXX, ZBTB22, TAPBP
|Feature=
|Evidence=PubMed ID:19837266
|Annotation=Risk or phenotype-associated allele, tested allele: unspecified; multiethnic minor allele is T per dbSNP Phenotype: In 114 cases and 414 controls (n = 528), univariate analysis of disease association showed OR = 0.79 for heterozygote, OR = 1.48 for homozygous, versus homozygous wild type, in ALL, with P(trend) OR = 1.12, p = 0.47 using an additive model. Study size: 528. Study population/ethnicity: Childhood acute lymphoblastic leukemia (<=14 years) and healthy newborn controls (1988 to 1999) from South Wales in the United Kingdom. Significance metric(s): Non-significant finding p = 0.47. Type of association: CO.
|Drugs=
|Drug Classes=
|Diseases=Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Curated
|PharmGKB Accession ID=PA165110226
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2239839
|overall_frequency_n=31
|overall_frequency_d=128
|overall_frequency=0.242188
|n_genomes=19
|n_genomes_annotated=0
|n_haplomes=23
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}