{{Rsnum
|rsid=2240335
|Gene=PADI4
|Chromosome=1
|position=17348042
|Orientation=minus
|ReferenceAllele=A
|GMAF=0.4224
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
|Gene_s=PADI4
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 54.5 | 36.6 | 8.9
| HCB | 13.1 | 48.9 | 38.0
| JPT | 17.7 | 49.6 | 32.7
| YRI | 42.9 | 38.1 | 19.0
| ASW | 36.8 | 56.1 | 7.0
| CHB | 13.1 | 48.9 | 38.0
| CHD | 12.8 | 46.8 | 40.4
| GIH | 31.7 | 51.5 | 16.8
| LWK | 44.5 | 42.7 | 12.7
| MEX | 50.0 | 37.9 | 12.1
| MKK | 50.0 | 36.5 | 13.5
| TSI | 36.6 | 48.5 | 14.9
| HapMapRevision=28
}}{{Report GE
|PubMed=12833157
|Source=17265154
|AffyProbeset=SNP_A-8556874
|AffyOrientation=same
|AlleleA=G
|AlleleB=T
|onGW5=0
|rsid=2240335
|ancestral=G
|RiskPopulation=Japan
|RiskAllele=G
|CaseFreq=
|ControlFreq=
|OddsRatioHet=
|OddsRatioHom=
|OddsRatioAll=1.75
|Disease=Rheumatoid Arthritis
|DiseaseSymbol=RA
}}

rs2240335 is in linkage disequilibrium with a polymorphism that increases susceptibility to Rheumatoid Arthritis 1.75 times for carriers of the G allele {{PMID|12833157}}
{{ neighbor
| rsid = 2240338
| distance = 352
}}

{{PMID Auto GWAS
|PMID=21225715
|Trait=None
|Title=Genome-wide association study of rheumatoid arthritis in Korea: Population-specific loci as well as overlap with European susceptibility loci
|RiskAllele=
|Pval=2E-8
|OR=1.5000
|ORtxt=[NR]
}}

{{PMID Auto GWAS
|PMID=21505073
|Trait=None
|Title=The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.
|RiskAllele=
|Pval=2E-8
|OR=None
|ORtxt=None
}}

{{PMID Auto GWAS
|PMID=21452313
|Trait=None
|Title=Genome-wide association study of rheumatoid arthritis in Koreans: population-specific loci as well as overlap with European susceptibility loci.
|RiskAllele=
|Pval=2E-8
|OR=1.5000
|ORtxt=[NR]
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}