{{Rsnum
|rsid=2242480
|Gene=CYP3A4
|Chromosome=7
|position=99763843
|Orientation=plus
|GMAF=0.3338
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=CYP3A4
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 85.3 | 14.7 | 0.0
| HCB | 57.3 | 35.1 | 7.6
| JPT | 46.9 | 47.8 | 5.3
| YRI | 1.4 | 23.3 | 75.3
| ASW | 10.7 | 42.9 | 46.4
| CHB | 57.3 | 35.1 | 7.6
| CHD | 0.0 | 0.0 | 0.0
| GIH | 45.5 | 44.4 | 10.1
| LWK | 1.8 | 21.1 | 77.1
| MEX | 35.1 | 47.4 | 17.5
| MKK | 20.9 | 45.8 | 33.3
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}
[[rs2242480]] is a SNP in the [[CYP3A4]] gene.

The [[rs2242480]](T) allele defines the CYP3A4*_20239G>A variant.

{{PMID Auto
|PMID=21692828
|Title=The Population Pharmacokinetics of R and S-Warfarin: Effect of Genetic and Clinical Factors
|OA=1
}}

{{PMID Auto
|PMID=21902501
|Title=Genetic polymorphisms in CYP3A4 are associated with withdrawal symptoms and adverse reactions in methadone maintenance patients
}}

{{PMID Auto
|PMID=17615053
|Title=Polymorphisms in the cytochrome P450 genes CYP1A2, CYP1B1, CYP3A4, CYP3A5, CYP11A1, CYP17A1, CYP19A1 and colorectal cancer risk.
|OA=1
}}

{{PMID Auto
|PMID=18163429
|Title=Genetic polymorphisms in CYP17, CYP3A4, CYP19A1, SRD5A2, IGF-1, and IGFBP-3 and prostate cancer risk in African-American men: the Flint Men's Health Study.
|OA=1
}}

{{PMID Auto
|PMID=18504423
|Title=Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant response.
|OA=1
}}

{{PMID Auto
|PMID=18825162
|Title=Prediction of CYP3A4 enzyme activity using haplotype tag SNPs in African Americans.
|OA=1
}}

{{PMID Auto
|PMID=21071160
|Title=Analysis of 50 SNPs in CYP2D6, CYP2C19, CYP2C9, CYP3A4 and CYP1A2 by MALDI-TOF mass spectrometry in Chinese Han population.
}}

{{PMID Auto
|PMID=21199372
|Title=A functional polymorphism in the CYP3A4 gene is associated with increased risk of coronary heart disease in the Chinese Han population.
}}

{{PMID Auto
|PMID=22178823
|Title=[Distribution of variant alleles association with warfarin pharmacokinetics and pharmacodynamics in the Han population in China].
}}

{{PMID Auto
|PMID=22583563
|Title=Genetic and environmental predictors of serum 25-hydroxyvitamin D concentrations among middle-aged and elderly Chinese in Singapore.
|OA=1
}}

{{PMID Auto
|PMID=25217544
|Title=Fatal Methadone Toxicity: Potential Role of CYP3A4 Genetic Polymorphism
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}