{{Rsnum
|rsid=2243250
|Gene=IL4
|Chromosome=5
|position=132673462
|Orientation=plus
|GMAF=0.4844
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=IL4
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 74.3 | 23.9 | 1.8
| HCB | 5.1 | 41.9 | 52.9
| JPT | 7.1 | 40.2 | 52.7
| YRI | 4.1 | 32.7 | 63.3
| ASW | 19.3 | 49.1 | 31.6
| CHB | 5.1 | 41.9 | 52.9
| CHD | 6.4 | 36.7 | 56.9
| GIH | 80.2 | 16.8 | 3.0
| LWK | 0.0 | 36.4 | 63.6
| MEX | 36.8 | 47.4 | 15.8
| MKK | 23.1 | 44.9 | 32.1
| TSI | 77.5 | 18.6 | 3.9
| HapMapRevision=28
}}
[[rs2243250]] is a SNP in the [[IL4]] gene that is also known as the -589C>T SNP.

In 300 patients younger than 50 years the [[rs2243250]](T) allele was associated with a reduced risk of myocardial infarction (odds ratio 0.57, CI: 0.34-0.95). This result was replicated in another study, where carriers of one or two -589T alleles also had a reduced risk (odds ratio 0.67, CI: 0.47-0.95), with a strong protective effect of the -598T allele in homozygous -589T (odds ratio 0.33, CI: 0.10-1.05).{{PMID|18662263}}

{{ neighbor
| rsid = 2070874
| distance = 556
}}

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{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}