{{Rsnum
|rsid=2257167
|Gene=IFNAR1
|Chromosome=21
|position=33343393
|Orientation=plus
|ReferenceAllele=G
|MissenseAllele=C
|GMAF=0.2084
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|Gene_s=IFNAR1
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 1.6 | 25.0 | 73.4
| HCB | 11.1 | 46.7 | 42.2
| JPT | 9.1 | 36.4 | 54.5
| YRI | 3.2 | 25.4 | 71.4
| ASW | 0.0 | 0.0 | 0.0
| CHB | 11.1 | 46.7 | 42.2
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=19103527
|Title=Association of two variants of the interferon-alpha receptor-1 gene with the presentation of hepatitis B virus infection
}}

{{PMID Auto
|PMID=20565290
|Title=Persistent Effect of IFNAR-1 Genetic Polymorphism on the Long-Term Pathogenesis of Chronic HBV Infection
}}

{{PMID Auto
|PMID=15657875
|Title=Polymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosus.
|OA=1
}}

{{PMID Auto
|PMID=17668374
|Title=Combining evidence of natural selection with association analysis increases power to detect malaria-resistance variants.
|OA=1
}}

{{PMID Auto
|PMID=19434718
|Title=Variants in interferon-alpha pathway genes and response to pegylated interferon-Alpha2a plus ribavirin for treatment of chronic hepatitis C virus infection in the hepatitis C antiviral long-term treatment against cirrhosis trial.
|OA=1
}}

{{PMID Auto
|PMID=20811626
|Title=Genetic variants in inflammation-related genes are associated with radiation-induced toxicity following treatment for non-small cell lung cancer.
|OA=1
}}

{{GET Evidence
|gene=IFNAR1
|aa_change=Val168Leu
|aa_change_short=V168L
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2257167
|overall_frequency_n=1549
|overall_frequency_d=10758
|overall_frequency=0.143986
|n_genomes=14
|n_genomes_annotated=0
|n_haplomes=19
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.898
|nblosum100=0
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}