{{Rsnum
|rsid=2266780
|Gene=FMO3
|Chromosome=1
|position=171114102
|Orientation=plus
|GMAF=0.1299
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=FMO3
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 58.4 | 39.8 | 1.8
| HCB | 70.1 | 24.1 | 5.8
| JPT | 67.3 | 29.2 | 3.5
| YRI | 97.3 | 2.7 | 0.0
| ASW | 91.2 | 8.8 | 0.0
| CHB | 70.1 | 24.1 | 5.8
| CHD | 64.2 | 33.0 | 2.8
| GIH | 95.0 | 5.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 82.8 | 17.2 | 0.0
| MKK | 98.1 | 1.9 | 0.0
| TSI | 75.2 | 24.8 | 0.0
| HapMapRevision=28
}}{{omim
|id=136132
|rsnum=2266780
|variant=0015
}}

{{ClinVar
|rsid=2266780
|Reversed=0
|FwdREF=A
|FwdALT=G
|REF=A
|ALT=G
|RSPOS=171114102
|CHROM=1
|GMAF=0.1296
|dbSNPBuildID=100
|SSR=0
|SAO=1
|VP=0x050378000a0515051f110101
|GENEINFO=FMO3:2328
|GENE_NAME=FMO3
|GENE_ID=2328
|WGT=1
|VC=SNV
|CLNALLE=1
|CLNHGVS=NC_000001.11:g.171114102A>G
|CLNSRC=ClinVar; GeneReviews; OMIM Allelic Variant
|CLNORIGIN=1
|CLNSRCID=NM_001002294.2:c.923A>G; NBK1103; 136132.0015
|CLNSIG=255
|CLNCUI=C0342739
|CLNDBN=Trimethylaminuria, mild; Trimethylaminuria
|Disease=Trimethylaminuria
|CLNACC=RCV000017711.1; RCV000031948.1
|Tags=PM;TPA;PMC;S3D;SLO;NSM;REF;ASP;VLD;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD;OM
|CAF=0.8701; 0.1299
|CLNDSDB=GeneReviews:MedGen:OMIM:SNOMED_CT
|CLNDSDBID=NBK1103:C0342739:602079:237959005
|COMMON=1
}}

{{PMID Auto
|PMID=15858076
|Title=Discovery of novel flavin-containing monooxygenase 3 (FMO3) single nucleotide polymorphisms and functional analysis of upstream haplotype variants.
|OA=1
}}

{{PMID Auto
|PMID=18565990
|Title=Systematic biological prioritization after a genome-wide association study: an application to nicotine dependence.
|OA=1
}}

{{PMID Auto
|PMID=9536088
|Title=Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication.
}}

{{PMID Auto
|PMID=10485731
|Title=Mild trimethylaminuria caused by common variants in FMO3 gene.
}}

{{GET Evidence
|gene=FMO3
|aa_change=Glu308Gly
|aa_change_short=E308G
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2266780
|overall_frequency_n=1476
|overall_frequency_d=10758
|overall_frequency=0.1372
|n_genomes=16
|n_genomes_annotated=0
|n_haplomes=16
|n_articles=0
|n_articles_annotated=0
|qualityscore_in_silico=3
|qualitycomment_in_silico=Y
|gene_in_genetests=Y
|pph2_score=0.141
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=6
|autoscore=3
|n_web_uneval=10
}}

{{PMID Auto
|PMID=24165757
|Title=The association of cytochrome P450 genetic polymorphisms with sulfolane formation and the efficacy of a busulfan-based conditioning regimen in pediatric patients undergoing hematopoietic stem cell transplantation
}}

{{PMID Auto
|PMID=24173915
|Title=Effects of single nucleotide polymorphisms of FMO3 and FMO6 genes on pharmacokinetic characteristics of sulindac sulfide in premature labor
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}