{{Rsnum
|rsid=2267668
|Gene=PPARD
|Chromosome=6
|position=35410145
|Orientation=plus
|GMAF=0.1612
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=PPARD
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 67.3 | 29.2 | 3.5
| HCB | 63.5 | 30.7 | 5.8
| JPT | 65.2 | 32.1 | 2.7
| YRI | 79.6 | 18.4 | 2.0
| ASW | 77.2 | 21.1 | 1.8
| CHB | 63.5 | 30.7 | 5.8
| CHD | 44.0 | 45.0 | 11.0
| GIH | 67.3 | 30.7 | 2.0
| LWK | 75.5 | 22.7 | 1.8
| MEX | 87.9 | 12.1 | 0.0
| MKK | 78.2 | 19.9 | 1.9
| TSI | 64.7 | 31.4 | 3.9
| HapMapRevision=28
}}{{PMID|18252792}} [[rs1053049]], [[rs6902123]], and [[rs2267668]] in PPARD affect Lifestyle Intervention induced changes in overall adiposity, hepatic fat storage, and relative muscle mass. Our findings provide a mechanistic explanation for the involvement of these genetic variations in the development of insulin resistance and [[type-2 diabetes]].

{{ neighbor
| rsid = 2016520
| distance = 856
}}

{{omim
|desc=PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-DELTA; PPARD
|id=600409
|rsnum=2267668
}}

{{omim
|desc=PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR-GAMMA, COACTIVATOR 1, ALPHA;
|id=604517
|rsnum=2267668
}}
{{PMID Auto
|PMID=19681917
|Title=The role of genetic variation in peroxisome proliferator-activated receptors in the [[polycystic ovary syndrome]] (PCOS): an original case-control study followed by systematic review and meta-analysis of existing evidence
}}

{{PMID Auto
|PMID=17327385
|Title=Genetic variations in PPARD and PPARGC1A determine mitochondrial function and change in aerobic physical fitness and insulin sensitivity during lifestyle intervention.
}}

{{PMID Auto
|PMID=21331343
|Title=The myocyte expression of adiponectin receptors and PPARdelta is highly coordinated and reflects lipid metabolism of the human donors.
|OA=1
}}

{{PMID Auto
|PMID=23186209
|Title=Mitochondriogenesis genes and extreme longevity.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}