{{Rsnum
|rsid=2268578
|Gene=LUM
|Chromosome=12
|position=91107421
|Orientation=minus
|GMAF=0.3104
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=LUM
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 79.8 | 19.3 | 0.9
| HCB | 36.3 | 54.1 | 9.6
| JPT | 53.6 | 38.2 | 8.2
| YRI | 0.0 | 0.0 | 0.0
| ASW | 14.5 | 47.3 | 38.2
| CHB | 36.3 | 54.1 | 9.6
| CHD | 42.6 | 46.3 | 11.1
| GIH | 68.0 | 29.0 | 3.0
| LWK | 11.0 | 29.4 | 59.6
| MEX | 53.4 | 44.8 | 1.7
| MKK | 15.5 | 41.9 | 42.6
| TSI | 65.0 | 31.0 | 4.0
| HapMapRevision=28
}}
[[rs2268578]] is a SNP in the lumican [[LUM]] gene.

Two populations of patients with [[breast cancer]], comprising ~800 cases from the Mayo Clinic and ~4,500 cases from East Anglia, England, were analyzed for SNP associations in the decorin and lumican genes. [[rs2268578]] was associated with [[breast cancer]] in both populations; in combined analyses, the odds ratio for [[rs2268578]](C;T) was 1.1 (CI: 0.9-1.2) and 1.9 (CI: 1.3-2.8, p 2 df = 0.001) for homozygotes. {{PMID|19036156|OA=1
}}

{{PMID Auto
|PMID=19843670
|Title=Association of Breast Cancer Susceptibility Variants with Risk of Pancreatic Cancer
|OA=1
}}

{{PMID|20360993|OA=1
}} Candidate gene study to investigate the genetic determinants of normal variation in central corneal thickness.

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | Illumina Human 1M}}