{{Rsnum
|rsid=2269426
|Gene=TNXB
|Chromosome=6
|position=32108722
|Orientation=minus
|GMAF=0.3393
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=TNXB
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 36.3 | 47.8 | 15.9
| HCB | 51.8 | 40.9 | 7.3
| JPT | 38.9 | 47.8 | 13.3
| YRI | 45.9 | 47.3 | 6.8
| ASW | 45.6 | 45.6 | 8.8
| CHB | 51.8 | 40.9 | 7.3
| CHD | 53.2 | 41.3 | 5.5
| GIH | 39.6 | 46.5 | 13.9
| LWK | 64.2 | 33.0 | 2.8
| MEX | 51.7 | 37.9 | 10.3
| MKK | 69.7 | 28.4 | 1.9
| TSI | 27.5 | 49.0 | 23.5
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=19198610
|Trait=Plasma eosinophil count
|Title=Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction
|RiskAllele=T
|Pval=0.000003
|OR=4.60
|ORtxt=[2.7-6.6] % standard unit increase
}}

{{PharmGKB
|RSID=rs2269426
|Name_s=
|Gene_s=TNXB
|Feature=
|Evidence=PubMed ID:19198610; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction. (Initial Sample Size: 9,392 individuals; Replication Sample Size: 12,118 individuals); (Region: 6p21.32; Reported Gene(s): MHC; Risk Allele: rs2269426-T); (p-value= 0.000003).This variant is associated with Plasma eosinophil count.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164739960
}}

{{PMID Auto
|PMID=19860791
|Title=Genetic evidence for a role of IL33 in nasal polyposis.
}}

{{PMID Auto
|PMID=20369022
|Title=Candidate causal regulatory effects by integration of expression QTLs with complex trait genetic associations.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2269426
|overall_frequency_n=39
|overall_frequency_d=126
|overall_frequency=0.309524
|n_genomes=31
|n_genomes_annotated=0
|n_haplomes=34
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}