{{Rsnum
|rsid=227163
|Chromosome=1
|position=7901146
|Orientation=plus
|GMAF=0.3237
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 19.6 | 42.0 | 38.4
| HCB | 5.9 | 36.8 | 57.4
| JPT | 14.2 | 44.2 | 41.6
| YRI | 6.1 | 31.3 | 62.6
| ASW | 7.0 | 43.9 | 49.1
| CHB | 5.9 | 36.8 | 57.4
| CHD | 5.5 | 34.9 | 59.6
| GIH | 16.8 | 53.5 | 29.7
| LWK | 8.2 | 47.3 | 44.5
| MEX | 8.6 | 43.1 | 48.3
| MKK | 11.6 | 53.5 | 34.8
| TSI | 19.2 | 45.5 | 35.4
| HapMapRevision=28
}}One of 42 more SNPs associated with [[rheumatoid arthritis]] based on a meta-analysis of 30,000 patients, most with odds ratios of 1.01 - 1.2. {{doi|10.1038/nature12873}}

{{PMID Auto GWAS
  |PMID=24390342
  |Trait=Rheumatoid arthritis
  |Title=Genetics of rheumatoid arthritis contributes to biology and drug discovery.
  |RiskAllele=C
  |Pval=3E-9
  |OR=1.11
  |ORtxt=[1.08-1.16]
  }}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}