{{Rsnum
|rsid=2277339
|Gene=PRIM1
|Chromosome=12
|position=56752285
|Orientation=plus
|GMAF=0.1616
|Gene_s=PRIM1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(G;G)
|geno2=(G;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(G;G)
| geno2=(G;T)
| geno3=(T;T)
| CEU | 0.0 | 17.9 | 82.1
| HCB | 7.3 | 37.2 | 55.5
| JPT | 5.3 | 27.4 | 67.3
| YRI | 3.4 | 37.7 | 58.9
| ASW | 1.8 | 31.6 | 66.7
| CHB | 7.3 | 37.2 | 55.5
| CHD | 5.5 | 30.3 | 64.2
| GIH | 0.0 | 11.9 | 88.1
| LWK | 2.7 | 25.5 | 71.8
| MEX | 3.4 | 29.3 | 67.2
| MKK | 7.7 | 23.7 | 68.6
| TSI | 2.0 | 21.6 | 76.5
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=22267201
|Trait=None
|Title=Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
|RiskAllele=G
|Pval=2E-19
|OR=0.3800
|ORtxt=None
|OA=1
}}

{{PMID Auto
|PMID=18603647
|Title=Functional genetic polymorphisms and female reproductive disorders: Part I: Polycystic ovary syndrome and ovarian response.
|OA=1
}}

{{GET Evidence
|gene=PRIM1
|aa_change=Asp5Ala
|aa_change_short=D5A
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2277339
|overall_frequency_n=1225
|overall_frequency_d=9900
|overall_frequency=0.123737
|n_genomes=17
|n_genomes_annotated=0
|n_haplomes=20
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.913
|nblosum100=5
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23307926
|Title=A genome-wide association study of early menopause and the combined impact of identified variants.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}