{{Rsnum
|rsid=2280089
|Gene=ADAM33
|Chromosome=20
|position=3669480
|Orientation=plus
|GMAF=0.1364
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=ADAM33
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.9 | 24.8 | 74.3
| HCB | 0.7 | 12.4 | 86.9
| JPT | 1.8 | 25.7 | 72.6
| YRI | 0.0 | 19.7 | 80.3
| ASW | 0.0 | 19.3 | 80.7
| CHB | 0.7 | 12.4 | 86.9
| CHD | 0.9 | 16.5 | 82.6
| GIH | 2.0 | 23.8 | 74.3
| LWK | 5.5 | 33.6 | 60.9
| MEX | 0.0 | 14.3 | 85.7
| MKK | 0.0 | 0.0 | 0.0
| TSI | 1.0 | 33.3 | 65.7
| HapMapRevision=28
}}[[rs2280089]], a SNP in the [[ADAM33]] gene, has been linked to a predisposition to [[asthma]] and bronchial hyperresponsiveness. [PMID 12110844, PMID 14564349]

{{ neighbor
| rsid = 2280090
| distance = 78
}}

{{PMID Auto
|PMID=16519819
|Title=Analysis of polymorphisms in 16 genes in type 1 diabetes that have been associated with other immune-mediated diseases.
|OA=1
}}

{{PMID Auto
|PMID=17878941
|Title=ADAM33, a new candidate for psoriasis susceptibility.
|OA=1
}}

{{PMID Auto
|PMID=18778489
|Title=Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population.
|OA=1
}}

{{PMID Auto
|PMID=22583515
|Title=ADAM33 polymorphisms, smoking and asthma in Japanese women: the Kyushu Okinawa Maternal and Child Health Study.
}}

{{PMID Auto
|PMID=23380143
|Title=A disintegrin and metalloprotease 33 (ADAM33) gene polymorphisms and the risk of asthma: a meta-analysis.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}