{{Rsnum
|rsid=2280838
|Gene=SLC39A4
|Chromosome=8
|position=144416618
|Orientation=minus
|ReferenceAllele=G
|MissenseAllele=A
|GMAF=0.4803
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=SLC39A4
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 29.7 | 45.0 | 25.2
| HCB | 16.1 | 55.5 | 28.5
| JPT | 11.6 | 52.7 | 35.7
| YRI | 17.2 | 45.5 | 37.2
| ASW | 22.8 | 52.6 | 24.6
| CHB | 16.1 | 55.5 | 28.5
| CHD | 20.2 | 44.0 | 35.8
| GIH | 17.8 | 40.6 | 41.6
| LWK | 13.6 | 49.1 | 37.3
| MEX | 23.2 | 41.1 | 35.7
| MKK | 14.1 | 55.1 | 30.8
| TSI | 26.0 | 54.0 | 20.0
| HapMapRevision=28
}}

{{Venter SNP
|rsid=2280838
|allele=T
|frequency=0.5
|uid=1103652472442
|type=homozygous_SNP
|hugo=SLC39A4
|ensembl gene=ENSG00000147804
|ensembl transcript=ENST00000301305
|sift=TOLERATED
|disease=Defects in SLC39A4 are the cause of acrodermatitis enteropathica zinc-deficiency type (AEZ) (MIM:201100). AEZ is a rare autosomal recessive disease caused by the inability to absorb sufficient zinc. The clinicals features are growth retardation, immune-system dysfunction, alopecia, severe dermatitis, diarrhea and occasionally mental disorders.
}}

{{ neighbor
| rsid = 17855765
| distance = 674
}}

{{GET Evidence
|gene=SLC39A4
|aa_change=Ala58Thr
|aa_change_short=A58T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2280838
|overall_frequency_n=5596
|overall_frequency_d=10702
|overall_frequency=0.522893
|n_genomes=37
|n_genomes_annotated=0
|n_haplomes=47
|n_articles=0
|n_articles_annotated=0
|nblosum100=1
|autoscore=0
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Illumina Human 1M}}