{{Rsnum
|rsid=2281999
|Gene=UNC13B
|Chromosome=9
|position=35381507
|Orientation=minus
|GMAF=0.3972
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=UNC13B
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 9.2 | 46.2 | 44.6
| HCB | 20.0 | 46.7 | 33.3
| JPT | 18.2 | 34.1 | 47.7
| YRI | 41.9 | 41.9 | 16.1
| ASW | 0.0 | 0.0 | 0.0
| CHB | 20.0 | 46.7 | 33.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

{{PMID|18633107|OA=1
}} [[rs2281999]] and [[rs13293564]] (G/T) diabetic nephropathy [[type-1 diabetes]] case/control (1176/1323) study from 3 European populations

*odds ratio (OR) for DN associated with the TT genotype was 1.68 [95%CI, 1.29 - 2.19], p = 1.0 10(-4))

replicated in an independent population of 412 cases and 614 controls, (combined OR of 1.63 [95%CI, 1.30 - 2.05], p = 2.3 10(-5))

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}