{{Rsnum
|rsid=2283228
|Gene=KCNQ1
|Chromosome=11
|position=2828300
|Orientation=plus
|GMAF=0.1804
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|Gene_s=KCNQ1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 84.8 | 15.2 | 0.0
| HCB | 40.9 | 48.2 | 10.9
| JPT | 32.7 | 51.3 | 15.9
| YRI | 78.2 | 21.1 | 0.7
| ASW | 86.0 | 14.0 | 0.0
| CHB | 40.9 | 48.2 | 10.9
| CHD | 36.7 | 52.3 | 11.0
| GIH | 96.0 | 4.0 | 0.0
| LWK | 80.0 | 19.1 | 0.9
| MEX | 62.1 | 32.8 | 5.2
| MKK | 74.8 | 24.5 | 0.6
| TSI | 88.2 | 11.8 | 0.0
| HapMapRevision=28
}}

[http://www.nature.com/ng/journal/vaop/ncurrent/abs/ng.208.html nature] [[type-2 diabetes]] 
*[[rs2283228]] (additive model P = 3.1 times 10-12; OR = 1.26, 95% CI = 1.18â€“1.34).

{{PMID Auto
|PMID=19516902
|Title=The type 2 diabetes associated minor allele of rs2237895 KCNQ1 associates with reduced insulin release following an oral glucose load
|OA=1
}}

{{PMID Auto
|PMID=19575309
|Title=Association study of four variants in KCNQ1 with type 2 diabetes mellitus and premature coronary artery disease in a Chinese population
}}

{{omim
|desc=DIABETES MELLITUS, NONINSULIN-DEPENDENT; NIDDM
|id=125853
|rsnum=2283228
}}

{{PMID Auto
|PMID=22479571
|Title=Several Polymorphisms of KCNQ1 Gene Are Associated with Plasma Lipid Levels in General Chinese Populations
|OA=1
}}

{{PMID Auto
|PMID=22206064
|Title=KCNQ1 variants associate with type 2 diabetes in Malaysian Malay subjects
}}

{{PMID Auto
|PMID=18711366
|Title=SNPs in KCNQ1 are associated with susceptibility to type 2 diabetes in East Asian and European populations.
}}

{{PMID Auto
|PMID=19252135
|Title=Genetic variation in KCNQ1 associates with fasting glucose and beta-cell function: a study of 3,734 subjects comprising three ethnicities living in Singapore.
|OA=1
}}

{{PMID Auto
|PMID=19448982
|Title=Variants in KCNQ1 are associated with susceptibility to type 2 diabetes in the population of mainland China.
|OA=1
}}

{{PMID Auto
|PMID=19502414
|Title=Association of 18 confirmed susceptibility loci for type 2 diabetes with indices of insulin release, proinsulin conversion, and insulin sensitivity in 5,327 nondiabetic Finnish men.
|OA=1
}}

{{PMID Auto
|PMID=20701788
|Title=KCNQ1 gene polymorphisms are associated with lipid parameters in a Chinese Han population.
|OA=1
}}

{{PMID Auto
|PMID=23271129
|Title=Meta-analysis of the effect of KCNQ1 gene polymorphism on the risk of type 2 diabetes
}}

{{PMID Auto
|PMID=23786590
|Title=Common Variants in KCNQ1 Confer Increased Risk of Type 2 Diabetes and Contribute to the Diabetic Epidemic in East Asians: A Replication and Meta-Analysis
}}

{{PMID Auto
|PMID=22696034
|Title=KCNQ1 SNPS and susceptibility to diabetic nephropathy in East Asians with type 2 diabetes.
}}

{{PMID Auto
|PMID=23107108
|Title=Lack of association between genetic polymorphisms within KCNQ1 locus and type 2 diabetes in Tunisian Arabs.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}