{{Rsnum
|rsid=2287499
|Gene=WRAP53
|Chromosome=17
|position=7688850
|Orientation=minus
|ReferenceAllele=C
|MissenseAllele=G
|GMAF=0.3379
|Gene_s=TP53
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 6.2 | 20.0 | 73.8
| HCB | 11.4 | 43.2 | 45.5
| JPT | 6.8 | 34.1 | 59.1
| YRI | 84.1 | 15.9 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 11.4 | 43.2 | 45.5
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

{{PMID|17683073}} ER negative [[breast cancer]] association  [[rs2287499]], OR (95% CI) = 1.08 (0.95-1.23) for CG vs. CC and 1.60 (1.04-2.47) for GG vs. CC, p-trend = 0.01)  (OR (95% CI) per variant allele: 1.42 (1.18-1.71) p-trend = 0.00009).

{{PMID Auto
|PMID=17151932
|Title=Genetic variation in p53 and ATM haplotypes and risk of glioma and meningioma.
}}

{{PMID Auto
|PMID=17428325
|Title=Common variants in the ATM, BRCA1, BRCA2, CHEK2 and TP53 cancer susceptibility genes are unlikely to increase breast cancer risk.
|OA=1
}}

{{PMID Auto
|PMID=18978339
|Title=Large-scale evaluation of candidate genes identifies associations between DNA repair and genomic maintenance and development of benzene hematotoxicity.
|OA=1
}}

{{PMID Auto
|PMID=19276375
|Title=Single nucleotide polymorphisms in the TP53 region and susceptibility to invasive epithelial ovarian cancer.
|OA=1
}}

{{PMID Auto
|PMID=20386703
|Title=Association between DNA damage response and repair genes and risk of invasive serous ovarian cancer.
|OA=1
}}

{{PMID Auto
|PMID=25134915
|Title=Single-strand conformational polymorphism analysis of a common single nucleotide variation in WRAP53 gene, rs2287499, and evaluating its association in relation to breast cancer risk and prognosis among Iranian-Azeri population
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}