{{Rsnum
|rsid=2290400
|Gene=GSDMB
|Chromosome=17
|position=39909987
|Orientation=minus
|GMAF=0.4467
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=GSDMB
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 19.3 | 56.9 | 23.9
| HCB | 41.7 | 47.7 | 10.6
| JPT | 51.1 | 40.0 | 8.9
| YRI | 35.7 | 45.5 | 18.9
| ASW | 27.3 | 43.6 | 29.1
| CHB | 41.7 | 47.7 | 10.6
| CHD | 52.8 | 39.8 | 7.4
| GIH | 36.0 | 47.0 | 17.0
| LWK | 20.9 | 45.5 | 33.6
| MEX | 32.1 | 50.0 | 17.9
| MKK | 13.8 | 40.8 | 45.4
| TSI | 23.0 | 57.0 | 20.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19430480
|Trait=Type 1 diabetes
|Title=Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
|RiskAllele=
|Pval=6E-13
|OR=1.15
|ORtxt=[1.08-1.22]
|OA=1
}}

{{PMID Auto
|PMID=19426955
|Title=Genome-wide association analysis identifies PDE4D as an asthma-susceptibility gene.
|OA=1
}}

{{PMID Auto
|PMID=19714205
|Title=Genome-wide association study implicates chromosome 9q21.31 as a susceptibility locus for asthma in mexican children.
|OA=1
}}

{{PMID Auto
|PMID=19732864
|Title=Allele-specific chromatin remodeling in the ZPBP2/GSDMB/ORMDL3 locus associated with the risk of asthma and autoimmune disease.
|OA=1
}}

{{PMID Auto
|PMID=22626592
|Title=17q12-21 variants are associated with asthma and interact with active smoking in an adult population from the United Kingdom.
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2290400
|overall_frequency_n=57
|overall_frequency_d=128
|overall_frequency=0.445312
|n_genomes=33
|n_genomes_annotated=0
|n_haplomes=48
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}