{{Rsnum
|rsid=229541
|Chromosome=22
|position=37195278
|Orientation=minus
|GMAF=0.4371
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 33.9 | 48.2 | 17.9
| HCB | 2.9 | 38.0 | 59.1
| JPT | 22.3 | 32.1 | 45.5
| YRI | 7.5 | 33.3 | 59.2
| ASW | 14.3 | 42.9 | 42.9
| CHB | 2.9 | 38.0 | 59.1
| CHD | 4.8 | 45.7 | 49.5
| GIH | 0.0 | 0.0 | 0.0
| LWK | 16.5 | 46.8 | 36.7
| MEX | 23.2 | 53.6 | 23.2
| MKK | 19.9 | 48.1 | 32.1
| TSI | 26.0 | 59.0 | 15.0
| HapMapRevision=28
}}
{{PMID Auto GWAS
|PMID=18978792
|Trait=Type 1 diabetes
|Title=Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci
|RiskAllele=T
|Pval=2E-8
|OR=1.04
|ORtxt=[0.97-1.12]
|OA=1
}}

{{PMID Auto GWAS
|PMID=19430480
|Trait=Type 1 diabetes
|Title=Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
|RiskAllele=
|Pval=2E-7
|OR=NR
|ORtxt=NR
|OA=1
}}

{{omim
|desc=DIABETES MELLITUS, INSULIN-DEPENDENT; IDDM
|id=222100
|rsnum=229541
}}

{{PharmGKB
|RSID=rs229541
|Name_s=
|Gene_s=C1QTNF6
|Feature=
|Evidence=PubMed ID:18978792; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. (Initial Sample Size: 3,561 cases, 4,646 controls; Replication Sample Size: 6,225 cases, 6,946 controls, 3,064 trios); (Region: 22q13.1; Reported Gene: C1QTNF6; Risk Allele: rs229541-T) This variant is associated with Type 1 diabetes.
|Drugs=
|Drug Classes=
|Diseases=Diabetes Mellitus, Type 1
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740871
}}

{{PharmGKB
|RSID=rs229541
|Name_s=
|Gene_s=C1QTNF6
|Feature=
|Evidence=PubMed ID:18978792; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Meta-analysis of genome-wide association study data identifies additional type 1 diabetes risk loci. (Initial Sample Size: 3,561 cases, 4,646 controls; Replication Sample Size: 6,225 cases, 6,946 controls, 3,064 trios); (Region: 22q13.1; Reported Gene(s): C1QTNF6; Risk Allele: rs229541-T); (p-value= 0.00000002).This variant is associated with Type 1 diabetes.
|Drugs=
|Drug Classes=
|Diseases=Diabetes Mellitus; Diabetes Mellitus, Type 1
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740760
}}

{{PMID Auto
|PMID=19073967
|Title=Shared and distinct genetic variants in type 1 diabetes and celiac disease.
|OA=1
}}

{{PMID Auto
|PMID=19168599
|Title=Type 1 diabetes in the BB rat: a polygenic disease.
|OA=1
}}

{{PMID Auto
|PMID=19474294
|Title=Potential etiologic and functional implications of genome-wide association loci for human diseases and traits.
|OA=1
}}

{{PMID Auto
|PMID=19966805
|Title=The imprinted DLK1-MEG3 gene region on chromosome 14q32.2 alters susceptibility to type 1 diabetes.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs229541
|overall_frequency_n=67
|overall_frequency_d=128
|overall_frequency=0.523438
|n_genomes=44
|n_genomes_annotated=0
|n_haplomes=64
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{PMID Auto
|PMID=24367383
|Title=Evidence of Stage- and Age-Related Heterogeneity of Non-HLA SNPs and Risk of Islet Autoimmunity and Type 1 Diabetes: The Diabetes Autoimmunity Study in the Young
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}