{{Rsnum
|rsid=2298771
|Gene=SCN1A
|Chromosome=2
|position=166036278
|Orientation=minus
|GMAF=0.2144
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=LOC102724058,SCN1A
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 41.5 | 44.6 | 13.8
| HCB | 75.6 | 24.4 | 0.0
| JPT | 75.0 | 22.7 | 2.3
| YRI | 76.2 | 22.2 | 1.6
| ASW | 0.0 | 0.0 | 0.0
| CHB | 75.6 | 24.4 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto
|PMID=19694741
|Title=Differential role of sodium channels SCN1A and SCN2A gene polymorphisms with epilepsy and multiple drug resistance in the north Indian population
|OA=1
}}

{{PMID|17676998|OA=1
}} Imputation-based analysis of association studies: candidate regions and quantitative traits.

{{PMID|21881118|OA=1
}} Genetic variants and susceptibility to neurological complications following West Nile virus infection.

{{GET Evidence
|gene=SCN1A
|aa_change=Ala1056Thr
|aa_change_short=A1056T
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2298771
|overall_frequency_n=7785
|overall_frequency_d=10756
|overall_frequency=0.723782
|n_genomes=49
|n_genomes_annotated=0
|n_haplomes=78
|n_articles=0
|n_articles_annotated=0
|gene_in_genetests=Y
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=1
|autoscore=3
|n_web_uneval=3
}}

{{ClinVar
|ALT=T
|CAF=0.2144; 0.7856
|CHROM=2
|CLNACC=RCV000030432.1; RCV000079572.1
|CLNALLE=1
|CLNDBN=Generalized epilepsy with febrile seizures plus; AllHighlyPenetrant
|CLNDSDB=MedGen
|CLNDSDBID=C3502809; CN169374
|CLNHGVS=NC_000002.11:g.166892788C>T
|CLNSIG=2
|COMMON=1
|Disease=Generalized epilepsy with febrile seizures plus; AllHighlyPenetrant
|FwdALT=A
|FwdREF=G
|GENEINFO=SCN1A:6323
|GENE_ID=6323
|GENE_NAME=SCN1A
|REF=C
|RSPOS=166892788
|Reversed=1
|SAO=0
|SSR=0
|Tags=RV;PM;PMC;SLO;VLD;G5A;G5;HD;GNO;KGPhase1;KGPilot123;KGPROD;OTHERKG;PH3;LSD
|VC=SNV
|VP=0x05016800000017051f100100
|WGT=0
|dbSNPBuildID=100
|rsid=2298771
|CLNSRC=Emory University
|CLNSRCID=6737
}}

{{PMID Auto
|PMID=22591328
|Title=Effects of SCN1A and GABA receptor genetic polymorphisms on carbamazepine tolerability and efficacy in Chinese patients with partial seizures: 2-year longitudinal clinical follow-up.
}}

{{PMID Auto
|PMID=24337656
|Title=Case-control association study of polymorphisms in the voltage-gated sodium channel genes SCN1A, SCN2A, SCN3A, SCN1B, and SCN2B and epilepsy
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}