{{Rsnum
|rsid=2305948
|Gene=KDR
|Chromosome=4
|position=55113391
|Orientation=plus
|GMAF=0.1313
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=KDR
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 84.1 | 15.9 | 0.0
| HCB | 73.0 | 24.8 | 2.2
| JPT | 82.3 | 16.8 | 0.9
| YRI | 53.7 | 38.1 | 8.2
| ASW | 61.4 | 31.6 | 7.0
| CHB | 73.0 | 24.8 | 2.2
| CHD | 71.6 | 25.7 | 2.8
| GIH | 82.2 | 17.8 | 0.0
| LWK | 68.2 | 28.2 | 3.6
| MEX | 94.8 | 5.2 | 0.0
| MKK | 61.5 | 31.4 | 7.1
| TSI | 83.2 | 15.8 | 1.0
| HapMapRevision=28
}}
{{PMID Auto
|PMID=19520980
|Title=VEGF Receptor-2 Variants Are Associated With Susceptibility to Stroke and Recurrence
}}

{{PMID Auto
|PMID=19875757
|Title=Clinical relevance of vascular endothelial growth factor (VEGFA) and VEGF receptor (VEGFR2) gene polymorphism on the treatment outcome following imatinib therapy
}}

{{PMID Auto
|PMID=22015057
|Title=Single nucleotide polymorphism associations with response and toxic effects in patients with advanced renal-cell carcinoma treated with first-line sunitinib: a multicentre, observational, prospective study
}}

{{PMID Auto
|PMID=22129133
|Title=VEGFA and VEGFR2 genetic polymorphisms and survival in patients with diffuse large B cell lymphoma
}}

{{PMID Auto
|PMID=19953880
|Title=[Association of variants in the vascular endothelial growth factor receptor 2 gene and the risk of hemorrhagic stroke].
}}

{{PMID Auto
|PMID=20019880
|Title=Polymorphisms in the VEGFA and VEGFR-2 genes and neovascular age-related macular degeneration.
|OA=1
}}

{{PMID Auto
|PMID=20389299
|Title=Pazopanib-induced hyperbilirubinemia is associated with Gilbert's syndrome UGT1A1 polymorphism.
|OA=1
}}

{{PMID Auto
|PMID=20401335
|Title=Sickle Cell Disease in the Post Genomic Era: A Monogenic Disease with a Polygenic Phenotype.
|OA=1
}}

{{PMID Auto
|PMID=21257617
|Title=Association of polymorphisms/haplotypes of the genes encoding vascular endothelial growth factor and its KDR receptor with recurrent pregnancy loss.
}}

{{PMID Auto
|PMID=21791631
|Title=Pharmacogenetic angiogenesis profiling for first-line Bevacizumab plus oxaliplatin-based chemotherapy in patients with metastatic colorectal cancer.
|OA=1
}}

{{PMID Auto
|PMID=22274884
|Title=Association between genetic variations of vascular endothelial growth factor receptor 2 and glioma in the Chinese Han population.
}}

{{PMID Auto
|PMID=23030506
|Title=SINGLE NUCLEOTIDE POLYMORPHISM AND SERUM LEVELS OF VEGFR2 ARE ASSOCIATED WITH AGE RELATED MACULAR DEGENERATION
}}

{{GET Evidence
|gene=KDR
|aa_change=Val297Ile
|aa_change_short=V297I
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2305948
|overall_frequency_n=1570
|overall_frequency_d=10758
|overall_frequency=0.145938
|n_genomes=18
|n_genomes_annotated=0
|n_haplomes=20
|n_articles=0
|n_articles_annotated=0
|pph2_score=0.97
|nblosum100=-4
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23111153
|Title=Implication of VEGFR2 in systemic lupus erythematosus: a combined genetic and structural biological approach
}}

{{PMID Auto
|PMID=23102494
|Title=Vascular endothelial growth factor family gene polymorphisms in preeclampsia in Sinhalese women in Sri-Lanka.
}}

{{PMID Auto
|PMID=24886133
|Title=Kinase insert domain receptor/vascular endothelial growth factor receptor 2 (KDR) genetic variation is associated with ovarian hyperstimulation syndrome
}}

{{PMID Auto
|PMID=25128838
|Title=Minor association of kinase insert domain-containing receptor gene polymorphism (rs2071559) with myocardial infarction in Caucasians with type 2 diabetes mellitus: Case-control cross-sectional study
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}