{{Rsnum
|rsid=236114
|Gene=MCM8
|Chromosome=20
|position=5954739
|Orientation=minus
|GMAF=0.1079
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=MCM8
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 3.5 | 35.4 | 61.1
| HCB | 0.0 | 0.7 | 99.3
| JPT | 0.0 | 0.0 | 100.0
| YRI | 0.7 | 6.8 | 92.5
| ASW | 0.0 | 15.8 | 84.2
| CHB | 0.0 | 0.7 | 99.3
| CHD | 0.0 | 0.0 | 0.0
| GIH | 6.9 | 30.7 | 62.4
| LWK | 0.0 | 8.3 | 91.7
| MEX | 1.7 | 24.1 | 74.1
| MKK | 1.3 | 9.0 | 89.7
| TSI | 3.9 | 24.5 | 71.6
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19448619
|Trait=Menopause
|Title=Loci at chromosomes 13, 19 and 20 influence age at natural menopause.
|RiskAllele=A
|Pval=1E-10
|OR=0.50
|ORtxt=[0.34-0.65] years older
|OA=1
}}

{{omim
|id=612885
|rsnum=236114
}}

{{PMID Auto
|PMID=17186469
|Title=Mutations in the gene encoding the Wnt-signaling component R-spondin 4 (RSPO4) cause autosomal recessive anonychia.
|OA=1
}}

{{PMID Auto
|PMID=19664201
|Title=Genetic and genomic insights into age at natural menopause.
|OA=1
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs236114
|overall_frequency_n=8948
|overall_frequency_d=10758
|overall_frequency=0.831753
|n_genomes=53
|n_genomes_annotated=0
|n_haplomes=99
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23360674
|Title=Genetic variation may modify ovarian reserve in female childhood cancer survivors.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}