{{Rsnum
|rsid=2407992
|Gene=TLR8
|Chromosome=X
|position=12920993
|Orientation=plus
|ReferenceAllele=G
|GMAF=0.3356
|Gene_s=TLR8,TLR8-AS1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;G)
|geno3=(G;G)
|effect1=
|effect2=
|effect3=
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;G)
| geno3=(G;G)
| CEU | 24.6 | 23.1 | 52.3
| HCB | 73.3 | 15.6 | 11.1
| JPT | 68.2 | 22.7 | 9.1
| YRI | 95.2 | 1.6 | 3.2
| ASW | 0.0 | 0.0 | 0.0
| CHB | 73.3 | 15.6 | 11.1
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

A study of ~900 Danish subjects concluded that [[rs2407992]] showed the most significant association with atopic [[asthma]].{{PMID|18682521}}

{{PMID Auto
|PMID=21872627
|Title=Association of polymorphisms in TLR genes and in genes of the Toll-like receptor signaling pathway with cancer risk.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}