{{Rsnum
|rsid=242939
|Gene=CRHR1
|Chromosome=17
|position=45818213
|Orientation=minus
|GMAF=0.1033
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=CRHR1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 85.8 | 14.2 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 42.2 | 44.2 | 13.6
| ASW | 63.2 | 28.1 | 8.8
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 99.0 | 1.0 | 0.0
| LWK | 37.3 | 47.3 | 15.5
| MEX | 91.4 | 8.6 | 0.0
| MKK | 39.1 | 49.4 | 11.5
| TSI | 90.2 | 9.8 | 0.0
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs242939
|Name_s=CRHR1:rs242939
|Gene_s=CRHR1
|Feature=Intron
|Evidence=PubMed ID:15128701; PubMed ID:16113459; PubMed ID:16815632; PubMed ID:17258395
|Annotation=Haplotype tagging SNP.
|Drugs=
|Drug Classes=
|Diseases=
|Curation Level=Curated
|PharmGKB Accession ID=PA161145034
}}

{{PMID Auto
|PMID=15365580
|Title=Association of a corticotropin-releasing hormone receptor 1 haplotype and antidepressant treatment response in Mexican-Americans.
}}

{{PMID Auto
|PMID=19750552
|Title=Risk and resilience: genetic and environmental influences on development of the stress response.
|OA=1
}}

{{PMID Auto
|PMID=21172166
|Title=Pharmacogenetics of antidepressant response.
|OA=1
}}

{{PMID Auto
|PMID=22352735
|Title=Genotyping the CRHR1 rs242939 (A>G) Polymorphism by a One-Step Tetra Primer-Amplification Refractory Mutation System-Polymerase Chain Reaction.
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs242939
|overall_frequency_n=18
|overall_frequency_d=128
|overall_frequency=0.140625
|n_genomes=15
|n_genomes_annotated=0
|n_haplomes=21
|n_articles=0
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{PMID Auto
|PMID=23726670
|Title=Association of glucocorticoid and type 1 corticotropin-releasing hormone receptors gene variants and risk for depression during pregnancy and post-partum
}}

{{PMID Auto
|PMID=23529111
|Title=Negative life events and corticotropin-releasing-hormone receptor1 gene in recurrent major depressive disorder.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}