{{Rsnum
|rsid=2442728
|Chromosome=6
|position=31351578
|Orientation=minus
|GMAF=0.371
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;C)
|geno3=(C;C)
|effect1=
|effect2=
|effect3=
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;C)
| geno3=(C;C)
| CEU | 9.2 | 60.0 | 30.8
| HCB | 26.7 | 35.6 | 37.8
| JPT | 29.5 | 54.5 | 15.9
| YRI | 8.5 | 49.2 | 42.4
| ASW | 0.0 | 0.0 | 0.0
| CHB | 26.7 | 35.6 | 37.8
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

[[rs2442728]] is a SNP located in the MHC region, upstream of HLA-B and about 1.2 Mb telomeric of DRB1.

A study of 855 [[rheumatoid arthritis]] patients concluded that [[rs2442728]] was one of only two SNPs representing an additional susceptibility gene - in addition to HLA-DRB1 - within the MHC region.{{PMID|19116923}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}