{{Rsnum
|rsid=2491097
|Gene=INVS
|Chromosome=9
|position=100240169
|Orientation=plus
|ReferenceAllele=C
|MissenseAllele=T
|GMAF=0.004591
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=INVS
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 99.1 | 0.9 | 0.0
| HCB | 100.0 | 0.0 | 0.0
| JPT | 100.0 | 0.0 | 0.0
| YRI | 100.0 | 0.0 | 0.0
| ASW | 0.0 | 0.0 | 0.0
| CHB | 100.0 | 0.0 | 0.0
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 98.0 | 2.0 | 0.0
| HapMapRevision=28
}}{{Venter SNP
|rsid=2491097
|allele=T
|frequency=0.009
|uid=1103652140951
|type=heterozygous_SNP
|hugo=INVS
|ensembl gene=ENSG00000119509
|ensembl transcript=ENST00000262457
|sift=AFFECT FUNCTION
|disease=Defects in INVS are the cause of nephronophthisis 2 (NPHP2) (MIM:602088). NPHP2 is a recessive disorder characterized by chronic renal failure in children, including tubular basement membrane disruption and renal interstitial fibrosis and enlarged kidneys and widespread cyst development. Some patients also display situs inversus.
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}