{{Rsnum
|rsid=2523393
|Gene=LOC285830
|Chromosome=6
|position=29737882
|Orientation=minus
|GMAF=0.3944
|Gene_s=HLA-F-AS1
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 32.8 | 39.1 | 28.1
| HCB | 32.5 | 30.0 | 37.5
| JPT | 20.0 | 40.0 | 40.0
| YRI | 1.6 | 32.8 | 65.6
| ASW | 0.0 | 0.0 | 0.0
| CHB | 32.5 | 30.0 | 37.5
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19525953
|Trait=Multiple sclerosis
|Title=Meta-analysis of genome scans and replication identify CD6, IRF8 and TNFRSF1A as new multiple sclerosis susceptibility loci
|RiskAllele=A
|Pval=1E-17
|OR=1.28
|ORtxt=[1.18-1.39]
|OA=1
}}

{{PMID|20405052|OA=1
}} The effect of single nucleotide polymorphisms from genome wide association studies in multiple sclerosis on gene expression.

{{PMID|20593013|OA=1
}} A major histocompatibility Class I locus contributes to multiple sclerosis susceptibility independently from HLA-DRB1*15:01.

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2523393
|overall_frequency_n=40
|overall_frequency_d=128
|overall_frequency=0.3125
|n_genomes=28
|n_genomes_annotated=0
|n_haplomes=34
|n_articles=0
|n_articles_annotated=0
|in_gwas=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | HumanOmni1Quad}}