{{Rsnum
|rsid=25648
|Gene=VEGFA
|Chromosome=6
|position=43771240
|Orientation=plus
|GMAF=0.1286
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=VEGFA
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 72.6 | 19.5 | 8.0
| HCB | 83.9 | 16.1 | 0.0
| JPT | 72.3 | 23.2 | 4.5
| YRI | 88.4 | 10.9 | 0.7
| ASW | 86.0 | 14.0 | 0.0
| CHB | 83.9 | 16.1 | 0.0
| CHD | 89.9 | 9.2 | 0.9
| GIH | 77.2 | 21.8 | 1.0
| LWK | 89.1 | 10.9 | 0.0
| MEX | 63.8 | 32.8 | 3.4
| MKK | 87.2 | 12.2 | 0.6
| TSI | 71.6 | 22.5 | 5.9
| HapMapRevision=28
}}{{PMID Auto
|PMID=19692168
|Title=Genetic Susceptibility to Distinct Bladder Cancer Subphenotypes
|OA=1
}}

{{PharmGKB
|RSID=rs25648
|Name_s=
|Gene_s=VEGFA
|Feature=
|Evidence=PubMed ID:17319747
|Annotation=This variant in the promoter region of the VEGFA gene was associated with increased risk for bladder cancer in a large-scale evaluation study of SNPs in candidate genes for cancer in 1,086 cases and 1,033 controls in Spain.
|Drugs=
|Drug Classes=
|Diseases=Urinary Bladder Neoplasms
|Curation Level=Curated
|PharmGKB Accession ID=PA162355803
}}

{{PMID|16645995}} Vascular endothelial growth factor gene haplotypes in Kawasaki disease.

{{PMID|19308252|OA=1
}} Genetic variation in VEGF does not contribute significantly to the risk of congenital cardiovascular malformation.

{{PMID|19372140|OA=1
}} EGFR pathway polymorphisms and bladder cancer susceptibility and prognosis.

{{PMID|19587357|OA=1
}} A systematic meta-analysis of genetic association studies for diabetic retinopathy.

{{PMID|19755511|OA=1
}} The role of vascular endothelial growth factor SNPs as predictive and prognostic markers for major solid tumors.

{{PMID|20019880|OA=1
}} Polymorphisms in the VEGFA and VEGFR-2 genes and neovascular age-related macular degeneration.

{{PMID|20706635|OA=1
}} Human genetics of diabetic retinopathy: current perspectives.

{{PMID|21347390|OA=1
}} Genetics of VEGF serum variation in human isolated populations of cilento: importance of VEGF polymorphisms.

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs25648
|overall_frequency_n=898
|overall_frequency_d=7956
|overall_frequency=0.112871
|n_genomes=3
|n_genomes_annotated=0
|n_haplomes=3
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=2
|webscore=N
|n_web_uneval=10
}}

{{PMID Auto
|PMID=23264084
|Title=Positive association of the vascular endothelial growth factor-A +405 GG genotype and poor survival in stage I-II gastric cancer in the Northern Chinese population.
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}