{{Rsnum
|rsid=2576573
|Gene=PENK
|Chromosome=8
|position=56445416
|Orientation=plus
|GMAF=0.3664
|Gene_s=PENK
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 17.7 | 50.4 | 31.9
| HCB | 13.9 | 40.1 | 46.0
| JPT | 9.0 | 51.4 | 39.6
| YRI | 2.7 | 34.7 | 62.6
| ASW | 3.5 | 40.4 | 56.1
| CHB | 13.9 | 40.1 | 46.0
| CHD | 8.3 | 46.3 | 45.4
| GIH | 22.8 | 51.5 | 25.7
| LWK | 7.3 | 33.0 | 59.6
| MEX | 10.7 | 50.0 | 39.3
| MKK | 7.7 | 48.4 | 43.9
| TSI | 27.5 | 42.2 | 30.4
| HapMapRevision=28
}}{{PMID Auto
|PMID=22745721
|Title=Cannabis-Dependence Risk Relates to Synergism between Neuroticism and Proenkephalin SNPs Associated with Amygdala Gene Expression: Case-Control Study
|OA=1
}}

{{on chip | Illumina Human 1M}}