{{Rsnum
|rsid=2592887
|Chromosome=1
|position=159683149
|Orientation=minus
|GMAF=0.4789
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 21.6 | 44.1 | 34.2
| HCB | 29.9 | 52.2 | 17.9
| JPT | 51.8 | 38.2 | 10.0
| YRI | 26.9 | 48.3 | 24.8
| ASW | 29.8 | 43.9 | 26.3
| CHB | 29.9 | 52.2 | 17.9
| CHD | 26.9 | 50.9 | 22.2
| GIH | 15.2 | 48.5 | 36.4
| LWK | 35.8 | 42.2 | 22.0
| MEX | 17.5 | 47.4 | 35.1
| MKK | 26.3 | 50.6 | 23.1
| TSI | 19.8 | 33.7 | 46.5
| HapMapRevision=28
}}{{PharmGKB
|RSID=rs2592887
|Name_s=
|Gene_s=-
|Feature=
|Evidence=PubMed ID:18439552
|Annotation=In a GWAS of subjects from the PARC study (Pharmacogenomics and Risk of Cardiovascular Disease), this was one of the ten SNPs most strongly associated with plasma C-reactive protein levels.
|Drugs=
|Drug Classes=
|Diseases=Cardiovascular Diseases
|Curation Level=Curated
|PharmGKB Accession ID=PA162399729
}}

{{PMID Auto
|PMID=18216863
|Title=Genetic determinants of basal C-reactive protein expression in Filipino systemic lupus erythematosus families.
|OA=1
}}

{{PMID Auto
|PMID=18439548
|Title=Loci related to metabolic-syndrome pathways including LEPR,HNF1A, IL6R, and GCKR associate with plasma C-reactive protein: the Women's Genome Health Study.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2592887
|overall_frequency_n=59
|overall_frequency_d=128
|overall_frequency=0.460938
|n_genomes=43
|n_genomes_annotated=0
|n_haplomes=59
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}