{{Rsnum
|rsid=2609653
|Chromosome=8
|position=34379474
|Orientation=plus
|GMAF=0.05418
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 0.9 | 8.8 | 90.3
| HCB | 0.0 | 10.2 | 89.8
| JPT | 0.0 | 7.1 | 92.9
| YRI | 0.7 | 12.9 | 86.4
| ASW | 1.8 | 7.0 | 91.2
| CHB | 0.0 | 10.2 | 89.8
| CHD | 0.0 | 15.6 | 84.4
| GIH | 0.0 | 2.0 | 98.0
| LWK | 0.0 | 8.2 | 91.8
| MEX | 0.0 | 3.4 | 96.6
| MKK | 0.0 | 8.4 | 91.6
| TSI | 0.0 | 7.8 | 92.2
| HapMapRevision=28
}}
[[rs2609653]] has been reported in a large study to be associated with [[bipolar disorder]].

The risk allele (oriented to the dbSNP entry) is (C); the odds ratio associated with heterozygotes is 1.43 (CI 1.19-1.71), and for homozygotes, 3.62 (CI 1.26-10.44). {{PMID|17554300|OA=1
}}

{{PMID Auto GWAS
|PMID=21254220
|Trait=None
|Title=Propensity score-based nonparametric test revealing genetic variants underlying bipolar disorder.
|RiskAllele=
|Pval=0.000007
|OR=None
|ORtxt=None
|OA=1
}}

{{PMID Auto GWAS
  |PMID=23453885
  |Trait=Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined)
  |Title=Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis.
  |RiskAllele=T
  |Pval=3E-6
  |OR=1.13
  |ORtxt=[1.07-1.19]
  |OA=1
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}