{{Rsnum
|rsid=2660
|Gene=OAS1
|Chromosome=12
|position=112919637
|Orientation=plus
|GMAF=0.2176
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=OAS1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 40.7 | 46.9 | 12.4
| HCB | 55.9 | 33.8 | 10.3
| JPT | 69.0 | 28.3 | 2.7
| YRI | 100.0 | 0.0 | 0.0
| ASW | 84.2 | 15.8 | 0.0
| CHB | 55.9 | 33.8 | 10.3
| CHD | 60.2 | 33.3 | 6.5
| GIH | 47.9 | 42.7 | 9.4
| LWK | 0.0 | 0.0 | 0.0
| MEX | 66.7 | 29.8 | 3.5
| MKK | 92.3 | 7.7 | 0.0
| TSI | 31.4 | 49.0 | 19.6
| HapMapRevision=28
}}{{PMID Auto
|PMID=20079393
|Title=2'-5'-Oligoadenylate synthetase single-nucleotide polymorphisms and haplotypes are associated with variations in immune responses to rubella vaccine
|OA=1
}}

{{PMID Auto
|PMID=21638280
|Title=2'-5' oligoadenylate synthetase 1 polymorphism is associated with prostate cancer
|OA=1
}}

{{PMID Auto
|PMID=22710942
|Title=Evaluate the relationship between polymorphisms of OAS1 gene and susceptibility to chronic hepatitis C with high resolution melting analysis
}}

{{PMID Auto
|PMID=15732009
|Title=Variation in antiviral 2',5'-oligoadenylate synthetase (2'5'AS) enzyme activity is controlled by a single-nucleotide polymorphism at a splice-acceptor site in the OAS1 gene.
|OA=1
}}

{{PMID Auto
|PMID=16251468
|Title=Survey of allelic expression using EST mining.
|OA=1
}}

{{PMID Auto
|PMID=18518984
|Title=Genome-wide survey of allele-specific splicing in humans.
|OA=1
}}

{{PMID Auto
|PMID=19247438
|Title=Genetic variation in OAS1 is a risk factor for initial infection with West Nile virus in man.
|OA=1
}}

{{PMID Auto
|PMID=19956105
|Title=Reassessment of the type I diabetes association of the OAS1 locus.
|OA=1
}}

{{GET Evidence
|gene=OAS1
|aa_change=Gly397Arg
|aa_change_short=G397R
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2660
|overall_frequency_n=102
|overall_frequency_d=128
|overall_frequency=0.796875
|n_genomes=51
|n_genomes_annotated=0
|n_haplomes=85
|n_articles=0
|n_articles_annotated=0
|nblosum100=6
|autoscore=0
|webscore=N
}}

{{PMID Auto
|PMID=23133602
|Title=Pharmacogenetics of efficacy and safety of HCV treatment in HCV-HIV coinfected patients: significant associations with IL28B and SOCS3 gene variants.
|OA=1
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}