{{Rsnum
|rsid=2665390
|Gene=TIPARP
|Chromosome=3
|position=156679960
|Orientation=plus
|GMAF=0.06061
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=LOC102724343,TIPARP
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 0.0 | 13.3 | 86.7
| HCB | 0.7 | 5.9 | 93.4
| JPT | 0.0 | 4.5 | 95.5
| YRI | 0.7 | 17.9 | 81.4
| ASW | 0.0 | 12.3 | 87.7
| CHB | 0.7 | 5.9 | 93.4
| CHD | 0.0 | 7.3 | 92.7
| GIH | 1.0 | 12.0 | 87.0
| LWK | 0.0 | 9.2 | 90.8
| MEX | 0.0 | 6.9 | 93.1
| MKK | 0.0 | 13.9 | 86.1
| TSI | 0.0 | 10.9 | 89.1
| HapMapRevision=28
}}[[rs2665390]] is a SNP in chromosomal region 3q25, in the TCDD-inducible poly(ADP-ribose) polymerase [[TIPARP]] gene.

A genome-wide association study ultimately including over 10,000 [[ovarian cancer]] patients found statistically strong (p = 7.1 × 10e-8) evidence for slightly elevated risk associated with the [[rs2665390]](C) allele, with an odds ratio of 	1.24 (CI: 1.15–1.34) as calculated for the serous subtype (of ovarian cancer).{{PMID|20852632|OA=1
}}

{{PMID Auto
|PMID=22235027
|Title=Evaluation of microRNA expression profiles and their associations with risk alleles in lymphoblastoid cell lines of familial ovarian cancer.
|OA=1
}}

{{PMID Auto
|PMID=22253144
|Title=Ovarian cancer susceptibility alleles and risk of ovarian cancer in BRCA1 and BRCA2 mutation carriers.
|OA=1
}}

{{PMID Auto GWAS
  |PMID=23544013
  |Trait=Ovarian cancer in BRCA1 mutation carriers
  |Title=Genome-wide association study in BRCA1 mutation carriers identifies novel loci associated with breast and ovarian cancer risk.
  |RiskAllele=C
  |Pval=7E-6
  |OR=1.46
  |ORtxt=[1.25-1.71]
  |OA=1
}}

{{PMID Auto
|PMID=23133607
|Title=Associations between gene expression variations and ovarian cancer risk alleles identified from genome wide association studies.
|OA=1
}}

{{PMID Auto
|PMID=25173882
|Title=Replication Study for the Association of Seven Genome- Gwas-Identified Loci With Susceptibility to Ovarian Cancer in the Polish Population
}}
{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}