{{Rsnum
|rsid=267759
|Gene=LMBRD2
|Chromosome=5
|position=36137518
|Orientation=plus
|GMAF=0.1267
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=LMBRD2
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 0.0 | 0.9 | 99.1
| HCB | 9.5 | 43.1 | 47.4
| JPT | 7.1 | 48.2 | 44.6
| YRI | 2.7 | 22.4 | 74.8
| ASW | 3.5 | 12.3 | 84.2
| CHB | 9.5 | 43.1 | 47.4
| CHD | 10.2 | 44.4 | 45.4
| GIH | 0.0 | 5.0 | 95.0
| LWK | 0.0 | 16.4 | 83.6
| MEX | 3.4 | 15.5 | 81.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 5.9 | 94.1
| HapMapRevision=28
}}{{PMID Auto GWAS
|PMID=19176441
|Trait=Treatment response for acute lymphoblastic leukemia
|Title=Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia
|RiskAllele=A
|Pval=0.000007
|OR=3.23
|ORtxt=[1.52-6.87]
|OA=1
}}

{{PharmGKB
|RSID=rs267759
|Name_s=
|Gene_s=LMBRD2
|Feature=
|Evidence=PubMed ID:19176441
|Annotation=This variant is associated with end-of-induction minimal risidual disease (MRD) in childhood acute lymphoblastic leukemia (ALL) from 2 independent cohorts (GWAS result). Risk Allele: A, MAF= 0.05, combined P value= 6.78E-06.
|Drugs=
|Drug Classes=
|Diseases=Neoplasm, Residual; Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Curated
|PharmGKB Accession ID=PA162470159
}}

{{PharmGKB
|RSID=rs267759
|Name_s=
|Gene_s=LMBRD2
|Feature=
|Evidence=PubMed ID:19176441; Web Resource:http://www.genome.gov/gwastudies/
|Annotation=GWAS results: Genome-wide interrogation of germline genetic variation associated with treatment response in childhood acute lymphoblastic leukemia. (Initial Sample Size: 487 children; Replication Sample Size: NR); (Region: 5p13.2; Reported Gene(s): LMBRD2; Risk Allele: rs267759-A); (p-value= 0.000007).This variant is associated with Treatment response for acute lymphoblastic leukemia.
|Drugs=
|Drug Classes=
|Diseases=Precursor Cell Lymphoblastic Leukemia-Lymphoma
|Curation Level=Non-Curated
|PharmGKB Accession ID=PA164740027
}}

{{GET Evidence
|impact=pathogenic
|qualified_impact=Insufficiently evaluated pathogenic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs267759
|overall_frequency_n=113
|overall_frequency_d=128
|overall_frequency=0.882812
|n_genomes=54
|n_genomes_annotated=0
|n_haplomes=97
|n_articles=1
|n_articles_annotated=0
|in_gwas=Y
|in_pharmgkb=Y
|autoscore=2
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}