{{Rsnum
|rsid=27048
|Gene=SLC6A3
|Chromosome=5
|position=1412530
|Orientation=plus
|GMAF=0.3255
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=SLC6A3
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 32.7 | 43.4 | 23.9
| HCB | 69.3 | 27.7 | 2.9
| JPT | 83.2 | 15.9 | 0.9
| YRI | 45.6 | 47.6 | 6.8
| ASW | 36.8 | 49.1 | 14.0
| CHB | 69.3 | 27.7 | 2.9
| CHD | 73.4 | 23.9 | 2.8
| GIH | 36.6 | 47.5 | 15.8
| LWK | 49.1 | 38.2 | 12.7
| MEX | 50.0 | 37.9 | 12.1
| MKK | 58.1 | 35.5 | 6.5
| TSI | 30.4 | 59.8 | 9.8
| HapMapRevision=28
}}
[rs27048]], a SNP in the dopamine transporter [[SLC6A3]] gene, has been associated with more severe symptoms upon alcohol withdrawal, such as seizures, in a study of 250 Caucasian alcohol-dependent patients. Two haplotypes appear to be tagged by this SNP and a neighbor, [[rs27072]]. {{PMID|18070248}}

Variations in the DAT1 gene may affect the inattentive subtype of ADHD.{{PMID|20800641}}

{{PMID Auto
|PMID=16537431
|Title=A dopamine transporter gene functional variant associated with cocaine abuse in a Brazilian sample.
|OA=1
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}