{{Rsnum
|rsid=2760118
|Gene=ALDH5A1
|Chromosome=6
|position=24503362
|Orientation=minus
|GMAF=0.3067
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
|Gene_s=ALDH5A1
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 14.2 | 45.1 | 40.7
| HCB | 2.2 | 24.4 | 73.3
| JPT | 2.7 | 35.4 | 61.9
| YRI | 15.8 | 54.1 | 30.1
| ASW | 15.8 | 49.1 | 35.1
| CHB | 2.2 | 24.4 | 73.3
| CHD | 1.9 | 29.6 | 68.5
| GIH | 8.9 | 40.6 | 50.5
| LWK | 26.9 | 47.2 | 25.9
| MEX | 6.9 | 29.3 | 63.8
| MKK | 25.6 | 51.3 | 23.1
| TSI | 9.8 | 34.3 | 55.9
| HapMapRevision=28
}}Mutational spectrum of the succinate semialdehyde dehydrogenase (ALDH5A1) gene and functional analysis of 27 novel disease-causing mutations in patients with SSADH deficiency.{{PMID|14635103}} Reduced SSADH activity with T variant (83% of normal).

{{PMID|15514892|OA=1
}} A 77-kilobase region of chromosome 6p22.2 is associated with dyslexia in families from the United Kingdom and from the United States.

{{PMID|19164088|OA=1
}} Comparative genomics of aldehyde dehydrogenase 5a1 (succinate semialdehyde dehydrogenase) and accumulation of gamma-hydroxybutyrate associated with its deficiency.

{{GET Evidence
|gene=ALDH5A1
|aa_change=His180Tyr
|aa_change_short=H180Y
|impact=not reviewed
|qualified_impact=Insufficiently evaluated not reviewed
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2760118
|overall_frequency_n=4020
|overall_frequency_d=10758
|overall_frequency=0.373675
|n_genomes=31
|n_genomes_annotated=0
|n_haplomes=39
|n_articles=0
|n_articles_annotated=0
|qualityscore_in_silico=3
|qualitycomment_in_silico=Y
|gene_in_genetests=Y
|genetests_testable=Y
|genetests_reviewed=Y
|nblosum100=-1
|autoscore=3
|n_web_uneval=10
}}

{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}
{{on chip | Illumina Human 1M}}