{{Rsnum
|rsid=2779562
|Gene=GABBR2
|Chromosome=9
|position=98515399
|Orientation=plus
|GMAF=0.4421
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(C;C)
|geno2=(C;T)
|geno3=(T;T)
|Gene_s=GABBR2
}}{{ population diversity
| geno1=(C;C)
| geno2=(C;T)
| geno3=(T;T)
| CEU | 29.2 | 44.2 | 26.5
| HCB | 60.6 | 36.5 | 2.9
| JPT | 44.2 | 44.2 | 11.5
| YRI | 12.2 | 39.5 | 48.3
| ASW | 24.6 | 40.4 | 35.1
| CHB | 60.6 | 36.5 | 2.9
| CHD | 58.7 | 33.9 | 7.3
| GIH | 21.8 | 41.6 | 36.6
| LWK | 20.9 | 47.3 | 31.8
| MEX | 44.8 | 41.4 | 13.8
| MKK | 11.5 | 52.6 | 35.9
| TSI | 19.6 | 50.0 | 30.4
| HapMapRevision=28
}}{{PMID|15759211|OA=1
}} Associated with [[nicotine Dependence]] as part of several haplotypes, based on a study of 1,000+ subjects including both African-Americans and European-Americans.

The risk haplotype varies between populations. Among African-Americans, the haplotype C-C-G of [[rs2491397]]-[[rs2184026]]-[[rs3750344]] had a significant positive association with [[nicotine dependence]]. Among European-Americans, for [[rs1435252]]-[[rs3780422]]-[[rs2779562]]-[[rs3750344]], the C-A-C-A haplotype was positively associated with [[nicotine dependence]] while the T-A-T-A haplotype was negatively associated.{{PMID|15759211|OA=1
}}

{{omim
|id=607340
|desc=GAMMA-AMINOBUTYRIC ACID B RECEPTOR 2; GABBR2
|rsnum=2779562
}}

{{omim
|id=607340
|rsnum=2779562
|variant=0002
}}

{{omim
|id=607340
|rsnum=2779562
|variant=0003
}}

{{PMID Auto
|PMID=22309839
|Title=Association study of 45 candidate genes in nicotine dependence in Han Chinese
}}

{{on chip | 23andMe v1}}
{{on chip | 23andMe v2}}
{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}
{{on chip | Affy GenomeWide 6}}
{{on chip | Affy500k}}
{{on chip | FTDNA2}}
{{on chip | FTDNA}}
{{on chip | HumanOmni1Quad}}