{{Rsnum
|rsid=2781659
|Gene=ARG1
|Chromosome=6
|position=131570680
|Orientation=plus
|GMAF=0.4178
|Assembly=GRCh38
|GenomeBuild=38.1
|dbSNPBuild=141
|geno1=(A;A)
|geno2=(A;G)
|geno3=(G;G)
}}{{ population diversity
| geno1=(A;A)
| geno2=(A;G)
| geno3=(G;G)
| CEU | 47.6 | 36.5 | 15.9
| HCB | 53.3 | 37.8 | 8.9
| JPT | 37.8 | 44.4 | 17.8
| YRI | 8.1 | 38.7 | 53.2
| ASW | 0.0 | 0.0 | 0.0
| CHB | 53.3 | 37.8 | 8.9
| CHD | 0.0 | 0.0 | 0.0
| GIH | 0.0 | 0.0 | 0.0
| LWK | 0.0 | 0.0 | 0.0
| MEX | 0.0 | 0.0 | 0.0
| MKK | 0.0 | 0.0 | 0.0
| TSI | 0.0 | 0.0 | 0.0
| HapMapRevision=28
}}

{{PMID|18617639|OA=1
}} associated with bronchodilator response among a sample of 209 children and their parents participating in the Childhood [[Asthma]] Management Program, the minor allele was associated with lower BDR compared to the homozygous major allele

{{PharmGKB
|RSID=rs2781659
|Name_s=
|Gene_s=ARG1
|Feature=
|Evidence=PubMed ID:18617639
|Annotation=This variant is associated with acute response to inhaled ? agonists in both childhood and adult asthmatic patients.
|Drugs=budesonide; fluticasone propionate; nedocromil; salbutamol
|Drug Classes=
|Diseases=Asthma
|Curation Level=Curated
|PharmGKB Accession ID=PA162168088
}}

{{PMID Auto
|PMID=19281908
|Title=Roles of arginase variants, atopy, and ozone in childhood asthma.
|OA=1
}}

{{GET Evidence
|impact=pharmacogenetic
|qualified_impact=Insufficiently evaluated pharmacogenetic
|inheritance=unknown
|quality_scores=Array
|dbsnp_id=rs2781659
|overall_frequency_n=59
|overall_frequency_d=128
|overall_frequency=0.460938
|n_genomes=41
|n_genomes_annotated=0
|n_haplomes=55
|n_articles=1
|n_articles_annotated=0
|in_pharmgkb=Y
|autoscore=1
|webscore=N
}}

{{on chip | 23andMe v3}}
{{on chip | 23andMe v4}}